Intracranial Biodegradable Silica-Based Nimodipine Drug Release Implant for Treating Vasospasm in Subarachnoid Hemorrhage in an Experimental Healthy Pig and Dog Model
Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage. When administrated orally or intravenously, systemic hypotension is an undesirable side effect. Intracranial subarachnoid delivery of nimodipine during aneurysm clipping may be more eff...
Main Authors: | Janne Koskimäki, Miikka Tarkia, Tuula Ahtola-Sätilä, Lasse Saloranta, Outi Simola, Ari-Pekka Forsback, Aki Laakso, Janek Frantzén |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/715752 |
Similar Items
-
Intra-arterial nimodipine for the treatment of vasospasm due to aneurysmal subarachnoid hemorrhage
by: A. Chiriac, et al.
Published: (2016-12-01) -
Efficacy of intra-arterial nimodipine therapy in the treatment of vasospasm after subarachnoid hemorrhage
by: Vedat Açık
Published: (2020-06-01) -
The curative effect of cinepazide maleate and nimodipine in the treatment of cerebral vasospasm after subarachnoid hemorrhage
by: Cui-fen LIU, et al.
Published: (2013-10-01) -
Treatment of Intracranial Vasospasm Following Subarachnoid Hemorrhage
by: Andrew Michael Bauer, et al.
Published: (2014-05-01) -
Continuous Selective Intra-Arterial Application of Nimodipine in Refractory Cerebral Vasospasm due to Aneurysmal Subarachnoid Hemorrhage
by: Stephanie Ott, et al.
Published: (2014-01-01)