GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD
Genital and perigenital human papilomavirus (HPV) infection in children has an incidence of 1.8% and the most frequently identified viral types are HPV 6 and 11. The mechanism of transmission of HPV to the anogenital area in children is vertical or perinatal transmission from an HPV-infected mater...
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doaj-84f90df68a50493699b2a12e35fc5b5b2021-09-02T17:08:45ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752009-05-0158221922310.37897/RJP.2009.2.16GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILDCarmen Sălăvăstru0T. Cristodulo1M. Panduru2A. Colțoiu3G.S. Țiplica4Clinica II Dermatologie, Spitalul Clinic „Colentina“, București, UMF „Carol Davila“, BucureștiClinica II Dermatologie, Spitalul Clinic „Colentina“, BucureștiClinica II Dermatologie, Spitalul Clinic „Colentina“, BucureștiClinica II Dermatologie, Spitalul Clinic „Colentina“, BucureștiClinica II Dermatologie, Spitalul Clinic „Colentina“, București, UMF „Carol Davila“, BucureștiGenital and perigenital human papilomavirus (HPV) infection in children has an incidence of 1.8% and the most frequently identified viral types are HPV 6 and 11. The mechanism of transmission of HPV to the anogenital area in children is vertical or perinatal transmission from an HPV-infected maternal genital tract (most likely in children under three years of age), horizontal transmission by auto- or heteroinoculation from cutaneous or mucosal warts elsewhere, and transmission by sexual abuse. The authors present several cases of infants aged under 24 month old referred to the clinic for multiple papillary lesions mainly found in anogenital region, the external genitalia and contiguous mucous membranes which, due to chronic friction, result in papules that are less verrucous and vary in color from pink to brown. Neither patient presented sings of sexual abuse; VDRL, TPHA and anti-HIV Ab were negative in all cases. The therapeutic approach was very difficult because of the extensive affected area and the patients’ age. Initially, we used several applications of trichloracetic acid and electrodessication with very good results and a free of lesion mean period of two month. In one case the lesions reappeared and we combined several therapeutic modalities: podophyllin, electrodessication, cauterization, with good results. As a conclusion, treating extensive affected areas of HPV infection in children may be challenging and the need of repeated applications might be followed by side effects.https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2009-Nr.2/RJP_2009_2_Art-16.pdfhpv infectionchildgenital. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carmen Sălăvăstru T. Cristodulo M. Panduru A. Colțoiu G.S. Țiplica |
spellingShingle |
Carmen Sălăvăstru T. Cristodulo M. Panduru A. Colțoiu G.S. Țiplica GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD Romanian Journal of Pediatrics hpv infection child genital. |
author_facet |
Carmen Sălăvăstru T. Cristodulo M. Panduru A. Colțoiu G.S. Țiplica |
author_sort |
Carmen Sălăvăstru |
title |
GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD |
title_short |
GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD |
title_full |
GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD |
title_fullStr |
GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD |
title_full_unstemmed |
GENITAL AND PERIGENITAL HUMAN PAPILOMAVIRUS (HPV) INFECTION IN SMALL CHILD |
title_sort |
genital and perigenital human papilomavirus (hpv) infection in small child |
publisher |
Amaltea Medical Publishing House |
series |
Romanian Journal of Pediatrics |
issn |
1454-0398 2069-6175 |
publishDate |
2009-05-01 |
description |
Genital and perigenital human papilomavirus (HPV) infection in children has an incidence of 1.8% and the most
frequently identified viral types are HPV 6 and 11. The mechanism of transmission of HPV to the anogenital
area in children is vertical or perinatal transmission from an HPV-infected maternal genital tract (most likely in
children under three years of age), horizontal transmission by auto- or heteroinoculation from cutaneous or
mucosal warts elsewhere, and transmission by sexual abuse.
The authors present several cases of infants aged under 24 month old referred to the clinic for multiple
papillary lesions mainly found in anogenital region, the external genitalia and contiguous mucous membranes
which, due to chronic friction, result in papules that are less verrucous and vary in color from pink to brown.
Neither patient presented sings of sexual abuse; VDRL, TPHA and anti-HIV Ab were negative in all cases.
The therapeutic approach was very difficult because of the extensive affected area and the patients’ age.
Initially, we used several applications of trichloracetic acid and electrodessication with very good results and
a free of lesion mean period of two month. In one case the lesions reappeared and we combined several
therapeutic modalities: podophyllin, electrodessication, cauterization, with good results. As a conclusion,
treating extensive affected areas of HPV infection in children may be challenging and the need of repeated
applications might be followed by side effects. |
topic |
hpv infection child genital. |
url |
https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2009-Nr.2/RJP_2009_2_Art-16.pdf |
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