The mechanism of humoral immune response to allogeneic organ transplantation

The mechanism of humoral immune response to allogeneic organ transplantation

The problem of antibody-mediated rejection of donor organ remains extremely relevant. The main targets of the antibodies are mainly donor HLA-antigens (Human Leucocyte Antigens), expressed, in particular, by the cells of graft vascular endothelium. This review describes the mechanisms of the develop...

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Bibliographic Details
Main Authors:	A. S. Berkos, G. V. Nikolaev
Format:	Article
Language:	Russian
Published:	Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2017-06-01
Series:	Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:	humoral rejection allograft hla-antigens b-cell receptors germinal centers epitopes crossreactivity
Online Access:	https://journal.transpl.ru/vtio/article/view/762

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