Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired
Background and objective: Since ancient times, honey has been used due to its nutritional and therapeutic value. The role of honey has been acknowledged in the scientific literature however, its use has been controversially discussed and has not been well accepted in modern medicine especially for d...
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doaj-85109fca130c47d1b03ed50bc86f7c9c2020-11-24T22:10:02ZengElsevierSaudi Journal of Biological Sciences1319-562X2017-07-012451030103310.1016/j.sjbs.2016.12.020Honey and diabetes mellitus: Obstacles and challenges – Road to be repairedSultan Ayoub Meo0Mohammad Javed Ansari1Kamran Sattar2Habib Ullah Chaudhary3Waseem Hajjar4Saleh Alasiri5Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Plant Protection, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi ArabiaMedical Education, College of Medicine, King Saud University, Riyadh, Saudi ArabiaOrthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi ArabiaThoracic Surgery, College of Medicine, King Saud University, Riyadh, Saudi ArabiaObstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi ArabiaBackground and objective: Since ancient times, honey has been used due to its nutritional and therapeutic value. The role of honey has been acknowledged in the scientific literature however, its use has been controversially discussed and has not been well accepted in modern medicine especially for diabetic patients. This study aimed to investigate the role of honey in diabetic patients. Methods: In this study, we identified 107 research articles from data based search engines including “PubMed”, “ISI-Web of Science”, “Embase” and “Google Scholar”. The research papers were selected by using the primary key-terms including “Honey”, “Honey bee” and “Diabetes Mellitus”. The research documents in which “Honey” and “Diabetes Mellitus” were debated are included. After screening, we reviewed 66 papers and finally we selected 35 studies which met the inclusion criteria and the remaining documents were excluded. Results: This study investigated the preclinical, clinical, human and animal model studies on honey and diabetes mellitus and found that honey decreases the fasting serum glucose, increases the sting C-peptide and 2-h postprandial C-peptide. Although, there is a dearth of data and literature also contrary discussed the use of honey in diabetic patients. Conclusion: Honey decreases the fasting serum glucose, increases fasting C-peptide and 2-h postprandial C-peptide. Honey had low glycemic index and peak incremental index in diabetic patients. The use of honey in diabetic patients still has obstacles and challenges and needs more large sample sized, multi-center clinical controlled studies to reach better conclusions.http://www.sciencedirect.com/science/article/pii/S1319562X16302066HoneyDiabetes mellitusAnti-inflammatoryAntioxidant |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sultan Ayoub Meo Mohammad Javed Ansari Kamran Sattar Habib Ullah Chaudhary Waseem Hajjar Saleh Alasiri |
spellingShingle |
Sultan Ayoub Meo Mohammad Javed Ansari Kamran Sattar Habib Ullah Chaudhary Waseem Hajjar Saleh Alasiri Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired Saudi Journal of Biological Sciences Honey Diabetes mellitus Anti-inflammatory Antioxidant |
author_facet |
Sultan Ayoub Meo Mohammad Javed Ansari Kamran Sattar Habib Ullah Chaudhary Waseem Hajjar Saleh Alasiri |
author_sort |
Sultan Ayoub Meo |
title |
Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired |
title_short |
Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired |
title_full |
Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired |
title_fullStr |
Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired |
title_full_unstemmed |
Honey and diabetes mellitus: Obstacles and challenges – Road to be repaired |
title_sort |
honey and diabetes mellitus: obstacles and challenges – road to be repaired |
publisher |
Elsevier |
series |
Saudi Journal of Biological Sciences |
issn |
1319-562X |
publishDate |
2017-07-01 |
description |
Background and objective: Since ancient times, honey has been used due to its nutritional and therapeutic value. The role of honey has been acknowledged in the scientific literature however, its use has been controversially discussed and has not been well accepted in modern medicine especially for diabetic patients. This study aimed to investigate the role of honey in diabetic patients.
Methods: In this study, we identified 107 research articles from data based search engines including “PubMed”, “ISI-Web of Science”, “Embase” and “Google Scholar”. The research papers were selected by using the primary key-terms including “Honey”, “Honey bee” and “Diabetes Mellitus”. The research documents in which “Honey” and “Diabetes Mellitus” were debated are included. After screening, we reviewed 66 papers and finally we selected 35 studies which met the inclusion criteria and the remaining documents were excluded.
Results: This study investigated the preclinical, clinical, human and animal model studies on honey and diabetes mellitus and found that honey decreases the fasting serum glucose, increases the sting C-peptide and 2-h postprandial C-peptide. Although, there is a dearth of data and literature also contrary discussed the use of honey in diabetic patients.
Conclusion: Honey decreases the fasting serum glucose, increases fasting C-peptide and 2-h postprandial C-peptide. Honey had low glycemic index and peak incremental index in diabetic patients. The use of honey in diabetic patients still has obstacles and challenges and needs more large sample sized, multi-center clinical controlled studies to reach better conclusions. |
topic |
Honey Diabetes mellitus Anti-inflammatory Antioxidant |
url |
http://www.sciencedirect.com/science/article/pii/S1319562X16302066 |
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