Bio-Catalytic Activity of Novel <i>Mentha arvensis</i> Intervened Biocompatible Magnesium Oxide Nanomaterials

• Main Authors: Shah Faisal, Abdullah, Hasnain Jan, Sajjad Ali Shah, Sumaira Shah, Muhammad Rizwan, Nasib Zaman, Zahid Hussain, Muhammad Nazir Uddin, Nadia Bibi, Aishma Khattak, Wajid Khan, Arshad Iqbal, Muhammad Idrees, Rehana Masood
• Format: Article
• Language: English
• Published: MDPI AG 2021-06-01
• Series: Catalysts
• Subjects: <i>Mentha arvensis</i>; green synthesis; magnesium oxide; antibacterial; bio-compatible; anti-cancer
• Online Access: https://www.mdpi.com/2073-4344/11/7/780

In the present study <i>Mentha arvensis</i> medaited Magnesium oxide nanoparticles were synthesized by novel green route followed by advanced characterization via XRD, FTIR, UV, SEM, TEM, DLS and TGA. The mean grain size of 32.4 nm and crystallite fcc morphology were confirmed by X-ray diffractive analysis. Scanning and Transmission electron microscopy analysis revealed the spherical and elliptical morphologies of the biosynthesized nanoparticles. Particle surface charge of −16.1 mV were determined by zeta potential and zeta size of 30–120 nm via dynamic light scattering method. Fourier transform spectroscopic analysis revealed the possible involvement of functional groups in the plant extract in reduction of Mg²⁺ ions to Mg⁰. Furthermore, the antioxidant, anti-Alzheimer, anti-cancer, and anti-<i>H. pylori</i> activities were performed. The results revealed that MgO-NPs has significant anti-<i>H. pyloric</i> potential by giving ZOI of 17.19 ± 0.83 mm against <i>Helicobacter</i> <i>felis</i> followed by <i>Helicobacter</i> <i>suis</i>. MgO-NPs inhibited protein kinase enzyme up to 12.44 ± 0.72% at 5 mg/mL and thus showed eminent anticancer activity. Significant free radicals scavenging and hemocompatability was also shown by MgO-NPs. MgO-NPs also displayed good inhibition potential against Hela cell lines with maximum inhibition of 49.49 ± 1.18 at 400 µg/mL. Owing to ecofriendly synthesis, non-toxic and biocompatible nature, <i>Mentha arvensis</i> synthesized MgO-NPs can be used as potent antimicrobial agent in therapeutic applications.