Adaptive variation regulates the expression of the human SGK1 gene in response to stress.
The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of ge...
Main Authors: | Francesca Luca, Sonal Kashyap, Catherine Southard, Min Zou, David Witonsky, Anna Di Rienzo, Suzanne D Conzen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2679193?pdf=render |
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