Vitamin D supplementation improves serum markers associated with hepatic fibrogenesis in chronic hepatitis C patients: A randomized, double-blind, placebo-controlled study

Abstract Hepatic fibrosis is the net accumulation of matrix tissue components which controlled by pro-fibrolytic enzymes, matrix metalloproteinases (MMPs), and pro-fibrotic cytokine, TGF-β1, and enzymes, tissue inhibitors of MMPs (TIMPs). Vitamin D (VD) supplementation has been shown to reverse thes...

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Bibliographic Details
Main Authors: Piyawat Komolmit, Sayamon Kimtrakool, Sirinporn Suksawatamnuay, Kessarin Thanapirom, Kanita Chattrasophon, Panarat Thaimai, Chintana Chirathaworn, Yong Poovorawan
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09512-7

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