Distal symmetrical polyneuropathy due to organophosphate intoxication
While a cholinergic crisis picture is onset in intoxication of organophosphate compounds; a severe polyneuropathy mainly affecting the motor fibers is viewed lately following weeks. Cholinergic crisis may require intubation meanwhile lately onset neuropathy may be characterized by cranial nerve pals...
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Society of TURAZ AKADEMI
2017-09-01
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doaj-8556ca93d8a341dba9da821040f7e5c52020-11-24T21:54:11ZengSociety of TURAZ AKADEMI Medicine Science2147-06342017-09-01635889110.5455/medscience.2017.06.8634261131Distal symmetrical polyneuropathy due to organophosphate intoxicationSemih Alay0Mehmet Guney Senol1Tansel Kendirli2Erdem Togrol3Mehmet Saracoglu4Ankara Gulhane Egitim ve Arastirma Hastanesi, Noroloji AbD Istanbul Sultan Abdulhamit Han Egitim ve Arastirma Hastanesi, Noroloji Servisi Istanbul Sultan Abdulhamit Han Egitim ve Arastirma Hastanesi, Noroloji Servisi Istanbul Sultan Abdulhamit Han Egitim ve Arastirma Hastanesi, Noroloji Servisi Istanbul Sultan Abdulhamit Han Egitim ve Arastirma Hastanesi, Noroloji ServisiWhile a cholinergic crisis picture is onset in intoxication of organophosphate compounds; a severe polyneuropathy mainly affecting the motor fibers is viewed lately following weeks. Cholinergic crisis may require intubation meanwhile lately onset neuropathy may be characterized by cranial nerve palsies, a hazy vision, ataxia and skin paresthesia. Exposure to substance could be progressed by respiratory tract and skin. 20-year-old male patient with muscle weakness and thinning in the hands and legs was admitted to our outpatient clinic. In his story; he had suicidal drunk pesticide 6 months ago, hospitalized due to loss of consciousness, given respiratory support in the intensive care unit for following 11 days. During the following period, sensory disorders involving numbness and pain, and thinning in the arms and legs were onset. At nerve conduction study, axonal polyneuropathy was identified: sensory fibers were protected, motor conduction velocities and amplitudes were extremely decreased. At needle EMG studies widespread denervation potentials were recorded to be more pronounced in the distal muscle groups. In the discussed case; a cholinergic crisis picture occurred after exposure to toxic agents in the acute phase, the patient was observed as intubated for a while, in the subacute phase a polyneuropathy mostly located in the proximal muscles was onset and muscle atrophies have emerged in the late phase. In this writing, an organophosphate intoxication case in which cholinergic crisis was set in earlier days, polyneuropathy picture was seen on subacute stage and muscle atrophies were confirmed on following weeks was discussed. [Med-Science 2017; 6(3.000): 588-91]http://www.ejmanager.com/fulltextpdf.php?mno=261131Organophosphate intoxicationcholinergic crisispolyneuropathy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Semih Alay Mehmet Guney Senol Tansel Kendirli Erdem Togrol Mehmet Saracoglu |
spellingShingle |
Semih Alay Mehmet Guney Senol Tansel Kendirli Erdem Togrol Mehmet Saracoglu Distal symmetrical polyneuropathy due to organophosphate intoxication Medicine Science Organophosphate intoxication cholinergic crisis polyneuropathy |
author_facet |
Semih Alay Mehmet Guney Senol Tansel Kendirli Erdem Togrol Mehmet Saracoglu |
author_sort |
Semih Alay |
title |
Distal symmetrical polyneuropathy due to organophosphate intoxication |
title_short |
Distal symmetrical polyneuropathy due to organophosphate intoxication |
title_full |
Distal symmetrical polyneuropathy due to organophosphate intoxication |
title_fullStr |
Distal symmetrical polyneuropathy due to organophosphate intoxication |
title_full_unstemmed |
Distal symmetrical polyneuropathy due to organophosphate intoxication |
title_sort |
distal symmetrical polyneuropathy due to organophosphate intoxication |
publisher |
Society of TURAZ AKADEMI |
series |
Medicine Science |
issn |
2147-0634 |
publishDate |
2017-09-01 |
description |
While a cholinergic crisis picture is onset in intoxication of organophosphate compounds; a severe polyneuropathy mainly affecting the motor fibers is viewed lately following weeks. Cholinergic crisis may require intubation meanwhile lately onset neuropathy may be characterized by cranial nerve palsies, a hazy vision, ataxia and skin paresthesia. Exposure to substance could be progressed by respiratory tract and skin. 20-year-old male patient with muscle weakness and thinning in the hands and legs was admitted to our outpatient clinic. In his story; he had suicidal drunk pesticide 6 months ago, hospitalized due to loss of consciousness, given respiratory support in the intensive care unit for following 11 days. During the following period, sensory disorders involving numbness and pain, and thinning in the arms and legs were onset. At nerve conduction study, axonal polyneuropathy was identified: sensory fibers were protected, motor conduction velocities and amplitudes were extremely decreased. At needle EMG studies widespread denervation potentials were recorded to be more pronounced in the distal muscle groups. In the discussed case; a cholinergic crisis picture occurred after exposure to toxic agents in the acute phase, the patient was observed as intubated for a while, in the subacute phase a polyneuropathy mostly located in the proximal muscles was onset and muscle atrophies have emerged in the late phase. In this writing, an organophosphate intoxication case in which cholinergic crisis was set in earlier days, polyneuropathy picture was seen on subacute stage and muscle atrophies were confirmed on following weeks was discussed. [Med-Science 2017; 6(3.000): 588-91] |
topic |
Organophosphate intoxication cholinergic crisis polyneuropathy |
url |
http://www.ejmanager.com/fulltextpdf.php?mno=261131 |
work_keys_str_mv |
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