Improving structural variant clustering to reduce the negative effect of the breakpoint uncertainty problem
Abstract Background Structural variants (SVs) represent an important source of genetic variation. One of the most critical problems in their detection is breakpoint uncertainty associated with the inability to determine their exact genomic position. Breakpoint uncertainty is a characteristic issue o...
Main Authors: | Jan Geryk, Alzbeta Zinkova, Iveta Zedníková, Halina Simková, Vlastimil Stenzl, Marie Korabecna |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04374-3 |
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