Metabolic and Network Pharmacological Analyses of the Therapeutic Effect of Grona styracifolia on Calcium Oxalate-Induced Renal Injury

Metabolic and Network Pharmacological Analyses of the Therapeutic Effect of Grona styracifolia on Calcium Oxalate-Induced Renal Injury

Grona styracifolia (Osbeck) Merr. (GS), a popular folk medicine, is clinically applied to treat nephrolithiasis. In this study, a urinary metabolic analysis was performed in a mouse model of renal calcium oxalate (CaOx) crystal deposition to identify the differentially altered metabolites in mice wi...

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Bibliographic Details
Main Authors: Wei Chen, Yachen Si, Jin Cheng, Jiarong Ding, Hongxia Zhao, Wenrui Liu, Qishan Lin, Jiebin Hou, Zhiyong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
traditional medicine
biological network
metabolomics
integrative pharmacology
renal injury
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.652989/full

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