Clinical Investigation of Benign Asbestos Pleural Effusion
There is no detailed information about benign asbestos pleural effusion (BAPE). The aim of the study was to clarify the clinical features of BAPE. The criteria of enrolled patients were as follows: (1) history of asbestos exposure; (2) presence of pleural effusion determined by chest X-ray, CT, and...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | Pulmonary Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/416179 |
id |
doaj-857614e3bb6140bfaacf5e84e29b2146 |
---|---|
record_format |
Article |
spelling |
doaj-857614e3bb6140bfaacf5e84e29b21462020-11-24T23:18:06ZengHindawi LimitedPulmonary Medicine2090-18362090-18442015-01-01201510.1155/2015/416179416179Clinical Investigation of Benign Asbestos Pleural EffusionNobukazu Fujimoto0Kenichi Gemba1Keisuke Aoe2Katsuya Kato3Takako Yokoyama4Ikuji Usami5Kazuo Onishi6Keiichi Mizuhashi7Toshikazu Yusa8Takumi Kishimoto9Department of Medical Oncology, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Okayama 7028055, JapanDepartment of Medical Oncology, Yamaguchi-Ube Medical Center, 685 Higashikiwa, Ube 7550241, JapanDepartment of Radiology, Okayama University Hospital, 2-5-1 Shikatacho, Okayama 7008558, JapanDepartment of Respiratory Medicine, Asahi Rosai Hospital, 61 Hirakochokita, Owariasahi 4880875, JapanDepartment of Respiratory Medicine, Asahi Rosai Hospital, 61 Hirakochokita, Owariasahi 4880875, JapanDepartment of Respiratory Medicine, Kobe Rosai Hospital, 4-1-23 Kagoikedori, Chuoku, Kobe 6510053, JapanDepartment of Respiratory Medicine, Toyama Rosai Hospital, 992 Rokuromaru, Uozu 9370042, JapanDepartment of Thoracic Surgery, Chiba Rosai Hospital, 2-16 Tatsumidaihigashi, Ichihara 2900003, JapanDepartment of Internal Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Okayama 7028055, JapanThere is no detailed information about benign asbestos pleural effusion (BAPE). The aim of the study was to clarify the clinical features of BAPE. The criteria of enrolled patients were as follows: (1) history of asbestos exposure; (2) presence of pleural effusion determined by chest X-ray, CT, and thoracentesis; and (3) the absence of other causes of effusion. Clinical information was retrospectively analysed and the radiological images were reviewed. There were 110 BAPE patients between 1991 and 2012. All were males and the median age at diagnosis was 74 years. The median duration of asbestos exposure and period of latency for disease onset of BAPE were 31 and 48 years, respectively. Mean values of hyaluronic acid, adenosine deaminase, and carcinoembryonic antigen in the pleural fluid were 39,840 ng/mL, 23.9 IU/L, and 1.8 ng/mL, respectively. Pleural plaques were detected in 98 cases (89.1%). Asbestosis was present in 6 (5.5%) cases, rounded atelectasis was detected in 41 (37.3%) cases, and diffuse pleural thickening (DPT) was detected in 30 (27.3%) cases. One case developed lung cancer (LC) before and after BAPE. None of the cases developed malignant pleural mesothelioma (MPM) during the follow-up.http://dx.doi.org/10.1155/2015/416179 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nobukazu Fujimoto Kenichi Gemba Keisuke Aoe Katsuya Kato Takako Yokoyama Ikuji Usami Kazuo Onishi Keiichi Mizuhashi Toshikazu Yusa Takumi Kishimoto |
spellingShingle |
Nobukazu Fujimoto Kenichi Gemba Keisuke Aoe Katsuya Kato Takako Yokoyama Ikuji Usami Kazuo Onishi Keiichi Mizuhashi Toshikazu Yusa Takumi Kishimoto Clinical Investigation of Benign Asbestos Pleural Effusion Pulmonary Medicine |
author_facet |
Nobukazu Fujimoto Kenichi Gemba Keisuke Aoe Katsuya Kato Takako Yokoyama Ikuji Usami Kazuo Onishi Keiichi Mizuhashi Toshikazu Yusa Takumi Kishimoto |
author_sort |
Nobukazu Fujimoto |
title |
Clinical Investigation of Benign Asbestos Pleural Effusion |
title_short |
Clinical Investigation of Benign Asbestos Pleural Effusion |
title_full |
Clinical Investigation of Benign Asbestos Pleural Effusion |
title_fullStr |
Clinical Investigation of Benign Asbestos Pleural Effusion |
title_full_unstemmed |
Clinical Investigation of Benign Asbestos Pleural Effusion |
title_sort |
clinical investigation of benign asbestos pleural effusion |
publisher |
Hindawi Limited |
series |
Pulmonary Medicine |
issn |
2090-1836 2090-1844 |
publishDate |
2015-01-01 |
description |
There is no detailed information about benign asbestos pleural effusion (BAPE). The aim of the study was to clarify the clinical features of BAPE. The criteria of enrolled patients were as follows: (1) history of asbestos exposure; (2) presence of pleural effusion determined by chest X-ray, CT, and thoracentesis; and (3) the absence of other causes of effusion. Clinical information was retrospectively analysed and the radiological images were reviewed. There were 110 BAPE patients between 1991 and 2012. All were males and the median age at diagnosis was 74 years. The median duration of asbestos exposure and period of latency for disease onset of BAPE were 31 and 48 years, respectively. Mean values of hyaluronic acid, adenosine deaminase, and carcinoembryonic antigen in the pleural fluid were 39,840 ng/mL, 23.9 IU/L, and 1.8 ng/mL, respectively. Pleural plaques were detected in 98 cases (89.1%). Asbestosis was present in 6 (5.5%) cases, rounded atelectasis was detected in 41 (37.3%) cases, and diffuse pleural thickening (DPT) was detected in 30 (27.3%) cases. One case developed lung cancer (LC) before and after BAPE. None of the cases developed malignant pleural mesothelioma (MPM) during the follow-up. |
url |
http://dx.doi.org/10.1155/2015/416179 |
work_keys_str_mv |
AT nobukazufujimoto clinicalinvestigationofbenignasbestospleuraleffusion AT kenichigemba clinicalinvestigationofbenignasbestospleuraleffusion AT keisukeaoe clinicalinvestigationofbenignasbestospleuraleffusion AT katsuyakato clinicalinvestigationofbenignasbestospleuraleffusion AT takakoyokoyama clinicalinvestigationofbenignasbestospleuraleffusion AT ikujiusami clinicalinvestigationofbenignasbestospleuraleffusion AT kazuoonishi clinicalinvestigationofbenignasbestospleuraleffusion AT keiichimizuhashi clinicalinvestigationofbenignasbestospleuraleffusion AT toshikazuyusa clinicalinvestigationofbenignasbestospleuraleffusion AT takumikishimoto clinicalinvestigationofbenignasbestospleuraleffusion |
_version_ |
1725581910841753600 |