A paradigm shift in studies based on rheumatoid arthritis clinical registries
Clinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measur...
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The Korean Association of Internal Medicine
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doaj-857eb154bd474063945a6099899c860e2021-08-10T01:40:47ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482019-09-0134597498110.3904/kjim.2018.440170167A paradigm shift in studies based on rheumatoid arthritis clinical registriesSoo-Kyung Cho0Yoon-Kyoung Sung1 Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, KoreaClinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measures now play a significant role in the drug development process as study endpoints in clinical trials of new therapies, and this has led to increased interest in the patient's perspective, drug safety and treatment outcomes in clinical practice. In accordance with these needs, many prospective cohorts for RA patients and registries of biologic disease modifying anti-rheumatic drugs have been actively conducted in the United States and European and Asian countries. A gradual shift is taking place in the major outcomes of clinical research using these prospective cohorts and registries. This article will introduce representative registries for RA in each country set up in the early 2000s and will discuss future perspectives in clinical research on RA patients using such clinical registries.http://www.kjim.org/upload/pdf/kjim-2018-440.pdfarthritis, rheumatoidcohort studiesregistriespatients reported outcomesbig data |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Soo-Kyung Cho Yoon-Kyoung Sung |
spellingShingle |
Soo-Kyung Cho Yoon-Kyoung Sung A paradigm shift in studies based on rheumatoid arthritis clinical registries The Korean Journal of Internal Medicine arthritis, rheumatoid cohort studies registries patients reported outcomes big data |
author_facet |
Soo-Kyung Cho Yoon-Kyoung Sung |
author_sort |
Soo-Kyung Cho |
title |
A paradigm shift in studies based on rheumatoid arthritis clinical registries |
title_short |
A paradigm shift in studies based on rheumatoid arthritis clinical registries |
title_full |
A paradigm shift in studies based on rheumatoid arthritis clinical registries |
title_fullStr |
A paradigm shift in studies based on rheumatoid arthritis clinical registries |
title_full_unstemmed |
A paradigm shift in studies based on rheumatoid arthritis clinical registries |
title_sort |
paradigm shift in studies based on rheumatoid arthritis clinical registries |
publisher |
The Korean Association of Internal Medicine |
series |
The Korean Journal of Internal Medicine |
issn |
1226-3303 2005-6648 |
publishDate |
2019-09-01 |
description |
Clinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measures now play a significant role in the drug development process as study endpoints in clinical trials of new therapies, and this has led to increased interest in the patient's perspective, drug safety and treatment outcomes in clinical practice. In accordance with these needs, many prospective cohorts for RA patients and registries of biologic disease modifying anti-rheumatic drugs have been actively conducted in the United States and European and Asian countries. A gradual shift is taking place in the major outcomes of clinical research using these prospective cohorts and registries. This article will introduce representative registries for RA in each country set up in the early 2000s and will discuss future perspectives in clinical research on RA patients using such clinical registries. |
topic |
arthritis, rheumatoid cohort studies registries patients reported outcomes big data |
url |
http://www.kjim.org/upload/pdf/kjim-2018-440.pdf |
work_keys_str_mv |
AT sookyungcho aparadigmshiftinstudiesbasedonrheumatoidarthritisclinicalregistries AT yoonkyoungsung aparadigmshiftinstudiesbasedonrheumatoidarthritisclinicalregistries AT sookyungcho paradigmshiftinstudiesbasedonrheumatoidarthritisclinicalregistries AT yoonkyoungsung paradigmshiftinstudiesbasedonrheumatoidarthritisclinicalregistries |
_version_ |
1721213115402551296 |