Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives

Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives

Abstract Nature has evolved exquisite sensing mechanisms to detect cellular and environmental signals surrounding living organisms. These biosensors have been widely used to sense small molecules, detect environmental cues and diagnose disease markers. Metabolic engineers and synthetic biologists ha...

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Bibliographic Details
Main Authors: Xia Wan, Monireh Marsafari, Peng Xu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Microbial Cell Factories
Subjects:
Transcriptional factors
Sensors
Eukaryotic cells
Metabolic engineering
Intelligent biomanufacturing
Synthetic biology
Online Access:http://link.springer.com/article/10.1186/s12934-019-1111-3

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http://link.springer.com/article/10.1186/s12934-019-1111-3

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