Risk of Optic Pathway Glioma in Neurofibromatosis Type 1: No Evidence of Genotype–Phenotype Correlations in A Large Independent Cohort

Risk of Optic Pathway Glioma in Neurofibromatosis Type 1: No Evidence of Genotype–Phenotype Correlations in A Large Independent Cohort

The occurrence of optic pathway gliomas (OPGs) in children with neurofibromatosis type 1 (NF1) still raises many questions regarding screening and surveillance because of the lack of robust prognostic factors. Recent studies of an overall cohort of 381 patients have suggested that the genotype may b...

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Bibliographic Details
Main Authors: Giulia Melloni, Marica Eoli, Claudia Cesaretti, Donatella Bianchessi, Maria Cristina Ibba, Silvia Esposito, Giulietta Scuvera, Guido Morcaldi, Roberto Micheli, Elena Piozzi, Sabrina Avignone, Luisa Chiapparini, Chiara Pantaleoni, Federica Natacci, Gaetano Finocchiaro, and Veronica Saletti
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
key words: neurofibromatosis type 1
nf1 gene
optic pathway glioma
genotype–phenotype correlations
Online Access:https://www.mdpi.com/2072-6694/11/12/1838

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