Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.

Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.

APOBEC3s (A3s) are potent restriction factors of human immunodeficiency virus type 1/simian immunodeficiency viruses (HIV-1/SIV), and can repress cross-species transmissions of lentiviruses. HIV-1 originated from a zoonotic infection of SIV of chimpanzee (SIVcpz) to humans. However, the impact of hu...

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Bibliographic Details
Main Authors: Zeli Zhang, Qinyong Gu, Marc de Manuel Montero, Ignacio G Bravo, Tomas Marques-Bonet, Dieter Häussinger, Carsten Münk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5739507?pdf=render

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http://europepmc.org/articles/PMC5739507?pdf=render

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