Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India
BackgroundThe Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Korean Diabetes Association
2017-08-01
|
Series: | Diabetes & Metabolism Journal |
Subjects: | |
Online Access: | https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-386.pdf |
id |
doaj-85ee539f5ea642f8ac89de5c268ba2d6 |
---|---|
record_format |
Article |
spelling |
doaj-85ee539f5ea642f8ac89de5c268ba2d62020-11-24T22:21:09ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872017-08-0141538639210.4093/dmj.2017.41.5.386Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, IndiaAnu Mary Oommen0Vinod Joseph Abraham1Thirunavukkarasu Sathish2V. Jacob Jose3Kuryan George4Department of Community Health, Christian Medical College, Vellore, India.Department of Community Health, Christian Medical College, Vellore, India.Centre for Population Health Sciences, Nanyang Technological University, Singapore, Singapore.Department of Cardiology, Christian Medical College, Vellore, India.Department of Community Health, Christian Medical College, Vellore, India.BackgroundThe Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu, and compared it with other diabetes risk scores developed from India.MethodsWe used the data from 4,896 participants (30 to 64 years) of a cross-sectional study conducted in Vellore (2010 to 2012), to calculate the AMCDRS scores using age, family history, and waist circumference. Sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV), and the area under the receiver operating characteristic curve (AROC) were calculated for undiagnosed and total diabetes.ResultsOf the 4,896 individuals surveyed, 274 (5.6%) had undiagnosed diabetes and 759 (15.5%) had total diabetes. The AMCDRS, with an optimum cut-point of ≥4, identified 45.0% for further testing with 59.5% sensitivity, 60.5% specificity, 9.1% PPV, 95.8% NPV, and an AROC of 0.639 (95% confidence interval [CI], 0.608 to 0.670) for undiagnosed diabetes. The corresponding figures for total diabetes were 75.1%, 60.5%, 25.9%, 93.0%, and 0.731 (95% CI, 0.713 to 0.750), respectively. The AROC for the AMCDRS was not significantly different from that of the Indian Diabetes Risk Score, the Ramachandran or the Chaturvedi risk scores for total diabetes, but was significantly lower than the AROC of the Chaturvedi score for undiagnosed diabetes.ConclusionThe AMCDRS is a simple diabetes risk score that can be used to screen for undiagnosed and total diabetes in low-resource primary care settings in India. However, it probably requires recalibration to improve its performance for undiagnosed diabetes.https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-386.pdfDiabetesRisk scoreUndiagnosedUniversal screening |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anu Mary Oommen Vinod Joseph Abraham Thirunavukkarasu Sathish V. Jacob Jose Kuryan George |
spellingShingle |
Anu Mary Oommen Vinod Joseph Abraham Thirunavukkarasu Sathish V. Jacob Jose Kuryan George Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India Diabetes & Metabolism Journal Diabetes Risk score Undiagnosed Universal screening |
author_facet |
Anu Mary Oommen Vinod Joseph Abraham Thirunavukkarasu Sathish V. Jacob Jose Kuryan George |
author_sort |
Anu Mary Oommen |
title |
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India |
title_short |
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India |
title_full |
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India |
title_fullStr |
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India |
title_full_unstemmed |
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India |
title_sort |
performance of the achutha menon centre diabetes risk score in identifying prevalent diabetes in tamil nadu, india |
publisher |
Korean Diabetes Association |
series |
Diabetes & Metabolism Journal |
issn |
2233-6079 2233-6087 |
publishDate |
2017-08-01 |
description |
BackgroundThe Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu, and compared it with other diabetes risk scores developed from India.MethodsWe used the data from 4,896 participants (30 to 64 years) of a cross-sectional study conducted in Vellore (2010 to 2012), to calculate the AMCDRS scores using age, family history, and waist circumference. Sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV), and the area under the receiver operating characteristic curve (AROC) were calculated for undiagnosed and total diabetes.ResultsOf the 4,896 individuals surveyed, 274 (5.6%) had undiagnosed diabetes and 759 (15.5%) had total diabetes. The AMCDRS, with an optimum cut-point of ≥4, identified 45.0% for further testing with 59.5% sensitivity, 60.5% specificity, 9.1% PPV, 95.8% NPV, and an AROC of 0.639 (95% confidence interval [CI], 0.608 to 0.670) for undiagnosed diabetes. The corresponding figures for total diabetes were 75.1%, 60.5%, 25.9%, 93.0%, and 0.731 (95% CI, 0.713 to 0.750), respectively. The AROC for the AMCDRS was not significantly different from that of the Indian Diabetes Risk Score, the Ramachandran or the Chaturvedi risk scores for total diabetes, but was significantly lower than the AROC of the Chaturvedi score for undiagnosed diabetes.ConclusionThe AMCDRS is a simple diabetes risk score that can be used to screen for undiagnosed and total diabetes in low-resource primary care settings in India. However, it probably requires recalibration to improve its performance for undiagnosed diabetes. |
topic |
Diabetes Risk score Undiagnosed Universal screening |
url |
https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-386.pdf |
work_keys_str_mv |
AT anumaryoommen performanceoftheachuthamenoncentrediabetesriskscoreinidentifyingprevalentdiabetesintamilnaduindia AT vinodjosephabraham performanceoftheachuthamenoncentrediabetesriskscoreinidentifyingprevalentdiabetesintamilnaduindia AT thirunavukkarasusathish performanceoftheachuthamenoncentrediabetesriskscoreinidentifyingprevalentdiabetesintamilnaduindia AT vjacobjose performanceoftheachuthamenoncentrediabetesriskscoreinidentifyingprevalentdiabetesintamilnaduindia AT kuryangeorge performanceoftheachuthamenoncentrediabetesriskscoreinidentifyingprevalentdiabetesintamilnaduindia |
_version_ |
1725771925745041408 |