Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China
Wei Huang, Yan Zhang, Bai-Hua Shen, Shuo Wang, Hong-Zhou Meng, Xiao-Dong Jin Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Purpose: To compare the outcomes of health-related quality of life (HRQOL) in patients undergoing open...
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doaj-85ffebb022e142a29f1c015de57f34f22020-11-24T22:08:16ZengDove Medical PressCancer Management and Research1179-13222019-01-01Volume 1189990743642Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in ChinaHuang WZhang YShen BHWang SMeng HZJin XDWei Huang, Yan Zhang, Bai-Hua Shen, Shuo Wang, Hong-Zhou Meng, Xiao-Dong Jin Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Purpose: To compare the outcomes of health-related quality of life (HRQOL) in patients undergoing open (ORP), laparoscopic (LRP), or robot-assisted (RARP) radical prostatectomy.Patients and methods: We retrospectively analyzed 347 men with clinically localized prostate cancer treated with ORP (n=97), LRP (n=71), or RARP (n=179) by high-volume surgeons in our institution between January 2014 and December 2016. The primary endpoint was HRQOL including urinary incontinence and erectile dysfunction.Results: One year after surgery, 15.9% of men reported moderate to severe urinary incontinence (ORP 16.5%, LRP 15.4%, and RARP 15.7%), with only 4.6% using pads. There were no statistically significant differences in the ratios of no pad usage and urinary incontinence bother after 12 months postoperatively among the three groups. However, 67.7% of the men reported moderate to severe erectile dysfunction (ORP 66%, LRP 66.1%, and RARP 69.3%) 12 months after surgery. There was no statistically significant difference in the international index of erectile function-5 (IIEF-5) postoperatively among the different surgical groups. In the univariate and multivariate analyses, age at surgery, preoperative IIEF-5, and neurovascular bundle preservation were the risk factors for moderate to severe sexual bother. Interestingly, 16.1% of men with an erection hardness score of grade 3–4 were hesitant to become sexually active postoperatively.Conclusion: ORP, LRP, and RARP have similar early HRQOL outcomes with respect to urinary incontinence and erectile dysfunction. In contrast to urinary continence, erectile dysfunction is still a serious concern for patients who undergo radical prostatectomy. Keywords: erectile dysfunction, prostate cancer, radical prostatectomy, urinary incontinencehttps://www.dovepress.com/outcomes-of-health-related-quality-of-life-after-open-laparoscopic-or--peer-reviewed-article-CMARErectile DysfunctionProstate CancerRadical ProstatectomyUrinary Incontinence |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Huang W Zhang Y Shen BH Wang S Meng HZ Jin XD |
spellingShingle |
Huang W Zhang Y Shen BH Wang S Meng HZ Jin XD Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China Cancer Management and Research Erectile Dysfunction Prostate Cancer Radical Prostatectomy Urinary Incontinence |
author_facet |
Huang W Zhang Y Shen BH Wang S Meng HZ Jin XD |
author_sort |
Huang W |
title |
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China |
title_short |
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China |
title_full |
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China |
title_fullStr |
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China |
title_full_unstemmed |
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China |
title_sort |
outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in china |
publisher |
Dove Medical Press |
series |
Cancer Management and Research |
issn |
1179-1322 |
publishDate |
2019-01-01 |
description |
Wei Huang, Yan Zhang, Bai-Hua Shen, Shuo Wang, Hong-Zhou Meng, Xiao-Dong Jin Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Purpose: To compare the outcomes of health-related quality of life (HRQOL) in patients undergoing open (ORP), laparoscopic (LRP), or robot-assisted (RARP) radical prostatectomy.Patients and methods: We retrospectively analyzed 347 men with clinically localized prostate cancer treated with ORP (n=97), LRP (n=71), or RARP (n=179) by high-volume surgeons in our institution between January 2014 and December 2016. The primary endpoint was HRQOL including urinary incontinence and erectile dysfunction.Results: One year after surgery, 15.9% of men reported moderate to severe urinary incontinence (ORP 16.5%, LRP 15.4%, and RARP 15.7%), with only 4.6% using pads. There were no statistically significant differences in the ratios of no pad usage and urinary incontinence bother after 12 months postoperatively among the three groups. However, 67.7% of the men reported moderate to severe erectile dysfunction (ORP 66%, LRP 66.1%, and RARP 69.3%) 12 months after surgery. There was no statistically significant difference in the international index of erectile function-5 (IIEF-5) postoperatively among the different surgical groups. In the univariate and multivariate analyses, age at surgery, preoperative IIEF-5, and neurovascular bundle preservation were the risk factors for moderate to severe sexual bother. Interestingly, 16.1% of men with an erection hardness score of grade 3–4 were hesitant to become sexually active postoperatively.Conclusion: ORP, LRP, and RARP have similar early HRQOL outcomes with respect to urinary incontinence and erectile dysfunction. In contrast to urinary continence, erectile dysfunction is still a serious concern for patients who undergo radical prostatectomy. Keywords: erectile dysfunction, prostate cancer, radical prostatectomy, urinary incontinence |
topic |
Erectile Dysfunction Prostate Cancer Radical Prostatectomy Urinary Incontinence |
url |
https://www.dovepress.com/outcomes-of-health-related-quality-of-life-after-open-laparoscopic-or--peer-reviewed-article-CMAR |
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