Effect of Bexarotene on Platelet Activation and Apoptosis

Effect of Bexarotene on Platelet Activation and Apoptosis

Background/Aims: The retinoid X receptor (RXRs) stimulator Bexarotene ((4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl] benzoic acid) is used for the treatment of several malignancies. Bexarotene is at least in part effective by stimulation of apoptosis of tumor cells. Moreover, B...

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Bibliographic Details
Main Authors:	Hang Cao, Rosi Bissinger, Anja T. Umbach, Meinrad Gawaz, Florian Lang
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Collagen related peptide Platelet activation Degranulation Integrin Cytosolic Ca2+ concentration Caspase Phosphatidylserine Thrombin
Online Access:	http://www.karger.com/Article/FullText/478627

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