Anti-VEGF therapy in retinopathy of prematurity
Retinopathy of prematurity(ROP)is an immature proliferative retinal vascular disease that may lead to permanent blindness in preterm infant. Retinal laser photocoagulation is used for ablation of peripheral retina and treatment of ROP, however, it is destructive. Especially for the cases with lesion...
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doaj-86410f721e03474fb1926ea7ce4a96ff2020-11-25T03:53:58ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232020-11-0120111894189710.3980/j.issn.1672-5123.2020.11.11Anti-VEGF therapy in retinopathy of prematurityQin Peng0Jun-Yong Wang1Qiu-Ping Liu2Affiliated Eye Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, ChinaDepartment of Ophthalmology, the People's Hospital of Zhangshu City, Zhangshu 331200, Jiangxi Province, ChinaAffiliated Eye Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, ChinaRetinopathy of prematurity(ROP)is an immature proliferative retinal vascular disease that may lead to permanent blindness in preterm infant. Retinal laser photocoagulation is used for ablation of peripheral retina and treatment of ROP, however, it is destructive. Especially for the cases with lesions in Zone I region, retinal laser photocoagulation may cause severe complications. Recently, studies have demonstrated that vascular endothelial growth factor(VEGF)plays a causal role in the pathogenesis of ROP, and intravitreal injection of anti-VEGF agents can not only effectively impede ROP progression, but also gain timing for revascularization of a vascular retinal region. This article reviews the treatment indications, drug selection, injection site, dosage recommendation, follow-up of efficacy and complications of intravitreal injection of anti-VEGF agents in the treatment of ROP.http://ies.ijo.cn/cn_publish/2020/11/202011011.pdfretinopathy of prematurityvascular endothelial growth factoranti-vascular endothelial growth factor agents |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Qin Peng Jun-Yong Wang Qiu-Ping Liu |
spellingShingle |
Qin Peng Jun-Yong Wang Qiu-Ping Liu Anti-VEGF therapy in retinopathy of prematurity Guoji Yanke Zazhi retinopathy of prematurity vascular endothelial growth factor anti-vascular endothelial growth factor agents |
author_facet |
Qin Peng Jun-Yong Wang Qiu-Ping Liu |
author_sort |
Qin Peng |
title |
Anti-VEGF therapy in retinopathy of prematurity |
title_short |
Anti-VEGF therapy in retinopathy of prematurity |
title_full |
Anti-VEGF therapy in retinopathy of prematurity |
title_fullStr |
Anti-VEGF therapy in retinopathy of prematurity |
title_full_unstemmed |
Anti-VEGF therapy in retinopathy of prematurity |
title_sort |
anti-vegf therapy in retinopathy of prematurity |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
Guoji Yanke Zazhi |
issn |
1672-5123 1672-5123 |
publishDate |
2020-11-01 |
description |
Retinopathy of prematurity(ROP)is an immature proliferative retinal vascular disease that may lead to permanent blindness in preterm infant. Retinal laser photocoagulation is used for ablation of peripheral retina and treatment of ROP, however, it is destructive. Especially for the cases with lesions in Zone I region, retinal laser photocoagulation may cause severe complications. Recently, studies have demonstrated that vascular endothelial growth factor(VEGF)plays a causal role in the pathogenesis of ROP, and intravitreal injection of anti-VEGF agents can not only effectively impede ROP progression, but also gain timing for revascularization of a vascular retinal region. This article reviews the treatment indications, drug selection, injection site, dosage recommendation, follow-up of efficacy and complications of intravitreal injection of anti-VEGF agents in the treatment of ROP. |
topic |
retinopathy of prematurity vascular endothelial growth factor anti-vascular endothelial growth factor agents |
url |
http://ies.ijo.cn/cn_publish/2020/11/202011011.pdf |
work_keys_str_mv |
AT qinpeng antivegftherapyinretinopathyofprematurity AT junyongwang antivegftherapyinretinopathyofprematurity AT qiupingliu antivegftherapyinretinopathyofprematurity |
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1724475534610530304 |