To screen or not to screen for medullary thyroid cancer? This is (yet) the question. An illustrative case.

Medullary thyroid cancer (MTC) is a rare disease, often displaying an aggressive behavior and a poor prognosis. Serum calcitonin represents the most sensitive marker of MTC and its routine measurement in patients with thyroid nodules allows early detection of occult MTC and appropriate surgical cure...

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Bibliographic Details
Main Authors: Rosaria Ruggeri, Luca Giovannella, Francesco Trimarchi, Alfredo Campennì
Format: Article
Language:English
Published: Accademia Peloritana dei Pericolanti 2018-12-01
Series:Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche
Subjects:
Online Access:http://cab.unime.it/journals/index.php/APMB/article/view/2014
Description
Summary:Medullary thyroid cancer (MTC) is a rare disease, often displaying an aggressive behavior and a poor prognosis. Serum calcitonin represents the most sensitive marker of MTC and its routine measurement in patients with thyroid nodules allows early detection of occult MTC and appropriate surgical cure.Here we report on a 55-yr-old woman with a long-standing goiter, autonomously functioning thyroid nodules and subclinical thyrotoxicosis, who was diagnosed with MTC at an early stage by means of calcitoninscreening. This rare case highlights the importance of performing routine calcitonin measurementin thyroid nodules.
ISSN:0365-0294
1828-6550