Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect

Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect

Xi Yang,1,2,* Bo Fan,3,* Wei Gao,4,5,* Liping Li,2 Tingting Li,3 Jinghua Sun,2 Xiaoyang Peng,2 Xiaoyan Li,2 Zhenjun Wang,2 Binquan Wang,4,5 Ruiping Zhang,2 Jun Xie1 1Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi, People’s Republic of China; 2...

Full description

Bibliographic Details
Main Authors:	Yang X, Fan B, Gao W, Li L, Li T, Sun J, Peng X, Li X, Wang Z, Wang B, Zhang R, Xie J
Format:	Article
Language:	English
Published:	Dove Medical Press 2018-07-01
Series:	International Journal of Nanomedicine
Subjects:	melanin poly-L-lysine photothermal effect endosomal escape siRNA delivery
Online Access:	https://www.dovepress.com/enhanced-endosomal-escape-by-photothermal-activation-for-improved-smal-peer-reviewed-article-IJN

Similar Items

Multi-functional Bio-synthetic Hybrid Nanostructures for Enhanced Cellular Uptake, Endosomal Escape and Targeted Delivery Toward Diagnostics and Therapeutics
by: Shrestha, Ritu 1984-
Published: (2013)

Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system
by: Xiang B, et al.
Published: (2017-03-01)

Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
by: Thakur Ajit, et al.
Published: (2012-06-01)

Photothermally Triggered Endosomal Escape and Its Influence on Transfection Efficiency of Gold-Functionalized JetPEI/pDNA Nanoparticles
by: Lotte M. P. Vermeulen, et al.
Published: (2018-08-01)

Tailoring Iron Oxide Nanoparticles for Efficient Cellular Internalization and Endosomal Escape
by: Laura Rueda-Gensini, et al.
Published: (2020-09-01)

Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA
by: Zang X, et al.
Published: (2016-08-01)

Non-viral Delivery of Nucleic Acids: Insight Into Mechanisms of Overcoming Intracellular Barriers
by: Mikhail Durymanov, et al.
Published: (2018-08-01)

Breaking in and busting out: cell-penetrating peptides and the endosomal escape problem
by: LeCher Julia C., et al.
Published: (2017-09-01)

A Smart pH-Sensitive Delivery System for Enhanced Anticancer Efficacy via Paclitaxel Endosomal Escape
by: Yihua Yang, et al.
Published: (2019-01-01)

Layer by Layer Assembled Chitosan-Coated Gold Nanoparticles for Enhanced siRNA Delivery and Silencing
by: Elnaz Shaabani, et al.
Published: (2021-01-01)

Toward the Selection of Cell Targeting Aptamers with Extended Biological Functionalities to Facilitate Endosomal Escape of Cargoes
by: Kwaku D. Tawiah, et al.
Published: (2017-08-01)

Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside
by: Muhammad Imran Sajid, et al.
Published: (2020-10-01)

Nanocarriers for Protein Delivery to the Cytosol: Assessing the Endosomal Escape of Poly(Lactide-co-Glycolide)-Poly(Ethylene Imine) Nanoparticles
by: Marianna Galliani, et al.
Published: (2019-04-01)

Melanin-Like Nanomedicine in Photothermal Therapy Applications
by: Yale Yue, et al.
Published: (2021-01-01)

Improving the Endosomal Escape of Cell-Penetrating Peptides and Their Cargos: Strategies and Challenges
by: Jean-Philippe Pellois, et al.
Published: (2012-11-01)

Poly(lysine) Dendrimers Form Complexes with siRNA and Provide Its Efficient Uptake by Myeloid Cells: Model Studies for Therapeutic Nucleic Acid Delivery
by: Michał Gorzkiewicz, et al.
Published: (2020-04-01)

siRNA-loaded poly(histidine-arginine)6-modified chitosan nanoparticle with enhanced cell-penetrating and endosomal escape capacities for suppressing breast tumor metastasis
by: Sun P, et al.
Published: (2017-04-01)

Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies
by: Hendrik Fuchs, et al.
Published: (2017-03-01)

Investigation of SNARE function in the early endosomal compartment
by: Bethani, Ioanna
Published: (2009)

The Role of Cholesterol on Triterpenoid Saponin-Induced Endolysosomal Escape of a Saporin-Based Immunotoxin
by: Wendy S. Smith, et al.
Published: (2020-11-01)

Augmenting the Efficacy of Immunotoxins and Other Targeted Protein Toxins by Endosomal Escape Enhancers
by: Hendrik Fuchs, et al.
Published: (2016-07-01)

Cationic Liposomes Carrying siRNA: Impact of Lipid Composition on Physicochemical Properties, Cytotoxicity and Endosomal Escape
by: Anna Lechanteur, et al.
Published: (2018-04-01)

Achieving efficient RNAi therapy: progress and challenges
by: Kun Gao, et al.
Published: (2013-07-01)

Silencing Bcl-2 Expression in Epithelial Cancer Cells Using “Smart” Particles
by: Yen-Ling Lin, et al.
Published: (2014-09-01)

Short-interfering RNAs as antivirals against rabies
by: Paulo Eduardo Brandão, et al.

Diving through Membranes: Molecular Cunning to Enforce the Endosomal Escape of Antibody-Targeted Anti-Tumor Toxins
by: David J. Flavell, et al.
Published: (2013-04-01)

Light-Triggerable Liposomes for Enhanced Endolysosomal Escape and Gene Silencing in PC12 Cells
by: Wenjie Chen, et al.
Published: (2017-06-01)

Natural Melanin-Based Nanoparticles With Combined Chemo/Photothermal/Photodynamic Effect Induce Immunogenic Cell Death (ICD) on Tumor
by: Ding Liu, et al.
Published: (2021-02-01)

Efficient Delivery of Macromolecules into Human Cells by Improving the Endosomal Escape Activity of Cell-Penetrating Peptides: Lessons Learned from dfTAT and its Analogs
by: Jason K. Allen, et al.
Published: (2018-07-01)

Nanoparticules lipidiques pH-sensibles basées sur une bascule moléculaire pour la délivrance intracytoplasmique de siRNA
by: Viricel, Warren
Published: (2017)

Curcumin-loaded nanoliposomes linked to homing peptides for integrin targeting and neuropilin-1-mediated internalization
by: Sogol Kangarlou, et al.
Published: (2017-01-01)

A Role for ETA(253-412) in Peptide-based Delivery of Therapeutic Molecules into Cells
by: Broad, Amaalia
Published: (2009)

A Role for ETA(253-412) in Peptide-based Delivery of Therapeutic Molecules into Cells
by: Broad, Amaalia
Published: (2009)

Enhanced lysosome escape mediated by 1,2-dicarboxylic-cyclohexene anhydride-modified poly-l-lysine dendrimer as a gene delivery system
by: Jianmin Shen, et al.
Published: (2020-11-01)

Tumor ablation using novel photothermal NaxWO3 nanoparticles against breast cancer osteolytic bone metastasis
by: Jie S, et al.
Published: (2019-09-01)

Silencing tumor necrosis factor-alpha in vitro from small interfering RNA-decorated titanium nanotube array can facilitate osteogenic differentiation of mesenchymal stem cells
by: Wang Z, et al.
Published: (2016-07-01)

T<sub>1</sub>-Positive Mn<sup>2+</sup>-Doped Multi-Stimuli Responsive poly(L-DOPA) Nanoparticles for Photothermal and Photodynamic Combination Cancer Therapy
by: Sumin Kang, et al.
Published: (2020-10-01)

Current Aspects of siRNA Bioconjugate for In Vitro and In Vivo Delivery
by: Wanyi Tai
Published: (2019-06-01)

Dynamic parent-of-origin effects on small interfering RNA expression in the developing maize endosperm
by: Xin, Mingming, et al.
Published: (2014)

Single-Stranded Phosphorothioated Regions Enhance Cellular Uptake of Cholesterol-Conjugated siRNA but Not Silencing Efficacy
by: Socheata Ly, et al.
Published: (2020-09-01)