Hesperidin, A Popular Antioxidant Inhibits Melanogenesis via Erk1/2 Mediated MITF Degradation

Hesperidin, A Popular Antioxidant Inhibits Melanogenesis via Erk1/2 Mediated MITF Degradation

Regulation of melanogenesis has been the focus of treatment for hyperpigmentary skin disorders. Although hesperidin is one of the most well-known, naturally occurring flavonoids with antioxidant and anti-inflammatory effect, its anti-melanogenic effect is not known. The present study aims to determi...

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Bibliographic Details
Main Authors: Heun Joo Lee, Woo Jin Lee, Sung Eun Chang, Ga-Young Lee
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
hesperidin
anti-melanogenesis
microphthalmia-associated transcription factor (MITF)
extracellular signal-regulated kinase 1/2 (Erk1/2)
antioxidant
Online Access:http://www.mdpi.com/1422-0067/16/8/18384

Internet

http://www.mdpi.com/1422-0067/16/8/18384

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