Prognostic value of patient‐derived xenograft engraftment in pediatric sarcomas

Prognostic value of patient‐derived xenograft engraftment in pediatric sarcomas

Abstract The goals of this work were to identify factors favoring patient‐derived xenograft (PDX) engraftment and study the association between PDX engraftment and prognosis in pediatric patients with Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma. We used immunodeficient mice to establish 30 sub...

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Main Authors: Helena Castillo‐Ecija, Guillem Pascual‐Pasto, Sara Perez‐Jaume, Claudia Resa‐Pares, Monica Vila‐Ubach, Carles Monterrubio, Ana Jimenez‐Cabaco, Merce Baulenas‐Farres, Oscar Muñoz‐Aznar, Noelia Salvador, Maria Cuadrado‐Vilanova, Nagore G Olaciregui, Leire Balaguer‐Lluna, Victor Burgueño, Francisco J Vicario, Alejandro Manzanares, Alicia Castañeda, Vicente Santa‐Maria, Ofelia Cruz, Veronica Celis, Andres Morales La Madrid, Moira Garraus, Maite Gorostegui, Margarita Vancells, Rosalia Carrasco, Lucas Krauel, Ferran Torner, Mariona Suñol, Cinzia Lavarino, Jaume Mora, Angel M Carcaboso
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:The Journal of Pathology: Clinical Research
Subjects:
patient‐derived xenograft
Ewing sarcoma
rhabdomyosarcoma
osteosarcoma
prognosis
Online Access:https://doi.org/10.1002/cjp2.210

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