Enhanced Wind-Up of the C-Fiber-Mediated Nociceptive Flexor Reflex Movement Following Painful Diabetic Neuropathy in Mice
We examined wind-up of the nociceptive flexor withdrawal responses in diabetic mice that had developed tactile allodynia after treatment with streptozotocin (STZ). In control and STZ-treated mice, simultaneous activation of Aδ- and C-fibers by electrical stimuli at C-fiber intensity delivered to the...
Main Authors: | Satoko Kimura, Mitsuo Tanabe, Motoko Honda, Hideki Ono |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2005-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319322704 |
Similar Items
-
Noxious Stimuli Evoke a Biphasic Flexor Reflex Composed of A δ-Fiber-Mediated Short-Latency and C-Fiber-Mediated Long-Latency Withdrawal Movements in Mice
by: Satoko Kimura, et al.
Published: (2004-01-01) -
Separate Recording of A-delta and C Fiber–Mediated Nociceptive Flexor Reflex Responses of Mouse Hindlimb Using Electromyography and the Characteristics of Wind-Up Appearing in the Responses
by: Satoko Kimura, et al.
Published: (2008-01-01) -
GABAB Receptors Do Not Mediate the Inhibitory Actions of Gabapentin on the Spinal Reflex in Rats
by: Shinobu Shimizu, et al.
Published: (2004-01-01) -
Involvement of Supraspinal Imidazoline Receptors and Descending Monoaminergic Pathways in Tizanidine-Induced Inhibition of Rat Spinal Reflexes
by: Yurika Kino, et al.
Published: (2005-01-01) -
Endogenous GABA Does Not Mediate the Inhibitory Effects of Gabapentin on Spinal Reflexes in Rats
by: Shinobu Shimizu, et al.
Published: (2004-01-01)