Inhibition of Aurora Kinase B activity disrupts development and differentiation of salivary glands

Inhibition of Aurora Kinase B activity disrupts development and differentiation of salivary glands

Abstract Little is known about the key molecules that regulate cell division during organogenesis. Here we determine the role of the cell cycle promoter aurora kinase B (AURKB) during development, using embryonic salivary glands (E-SGs) as a model. AURKB is a serine/threonine kinase that regulates k...

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Bibliographic Details
Main Authors: Abeer K. Shaalan, Tathyane H. N. Teshima, Abigail S. Tucker, Gordon B. Proctor
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-020-00393-w

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