Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs

Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs

In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well...

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Main Authors: Jafar Ezzati Nazhad Dolatabadi, Hadi Valizadeh, Hamed Hamishehkar
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Solid lipid nanoparticles
Colloidal carrier
Drug delivery
Gene delivery
Online Access:http://journals.tbzmed.ac.ir/APB/Abstract/APB_747_20140911170539
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spelling doaj-86959eb02b9c4abebd4f9cbd3053cb112020-11-24T22:48:10ZengTabriz University of Medical Sciences Advanced Pharmaceutical Bulletin2228-58812251-73082015-06-015215115910.15171/apb.2015.022Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent BreakthroughsJafar Ezzati Nazhad Dolatabadi0Hadi Valizadeh1Hamed Hamishehkar2Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well as proteins and nucleic acids. Therefore, SLNs offer great promise for controlled and site specific drug and gene delivery. This article includes general information about SLN structures and properties, production procedures, characterization. In addition, recent progress on development of drug and gene delivery systems using SLNs was reviewed.http://journals.tbzmed.ac.ir/APB/Abstract/APB_747_20140911170539Solid lipid nanoparticlesColloidal carrierDrug deliveryGene delivery
collection DOAJ
language English
format Article
sources DOAJ
author Jafar Ezzati Nazhad Dolatabadi
Hadi Valizadeh
Hamed Hamishehkar
spellingShingle Jafar Ezzati Nazhad Dolatabadi
Hadi Valizadeh
Hamed Hamishehkar
Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
Advanced Pharmaceutical Bulletin
Solid lipid nanoparticles
Colloidal carrier
Drug delivery
Gene delivery
author_facet Jafar Ezzati Nazhad Dolatabadi
Hadi Valizadeh
Hamed Hamishehkar
author_sort Jafar Ezzati Nazhad Dolatabadi
title Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
title_short Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
title_full Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
title_fullStr Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
title_full_unstemmed Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs
title_sort solid lipid nanoparticles as efficient drug and gene delivery systems: recent breakthroughs
publisher Tabriz University of Medical Sciences
series Advanced Pharmaceutical Bulletin
issn 2228-5881
2251-7308
publishDate 2015-06-01
description In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well as proteins and nucleic acids. Therefore, SLNs offer great promise for controlled and site specific drug and gene delivery. This article includes general information about SLN structures and properties, production procedures, characterization. In addition, recent progress on development of drug and gene delivery systems using SLNs was reviewed.
topic Solid lipid nanoparticles
Colloidal carrier
Drug delivery
Gene delivery
url http://journals.tbzmed.ac.ir/APB/Abstract/APB_747_20140911170539
work_keys_str_mv AT jafarezzatinazhaddolatabadi solidlipidnanoparticlesasefficientdrugandgenedeliverysystemsrecentbreakthroughs
AT hadivalizadeh solidlipidnanoparticlesasefficientdrugandgenedeliverysystemsrecentbreakthroughs
AT hamedhamishehkar solidlipidnanoparticlesasefficientdrugandgenedeliverysystemsrecentbreakthroughs
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