Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock
Abstract Sepsis results from a dyshomeostatic response to infection, which may lead to hyper or hypoimmune states. Monocytes are central regulators of the inflammatory response, but our understanding of their role in the genesis and resolution of sepsis is still limited. Here, we report a comprehens...
Main Authors: | Pedro Mendes de Azambuja Rodrigues, Richard Hemmi Valente, Giselle Villa Flor Brunoro, Helder Takashi Imoto Nakaya, Mariana Araújo-Pereira, Patricia Torres Bozza, Fernando Augusto Bozza, Monique Ramos de Oliveira Trugilho |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-94474-0 |
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