An Open Access Database of Licensed Cancer Drugs

• Main Authors: Pan Pantziarka, Rica Capistrano I, Arno De Potter, Liese Vandeborne, Gauthier Bouche
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2021-03-01
• Series: Frontiers in Pharmacology
• Subjects: drug repurposing; drug licensing; antineoplastic drugs; licensed drugs; database; list of cancer drugs
• Online Access: https://www.frontiersin.org/articles/10.3389/fphar.2021.627574/full

A global, comprehensive and open access listing of approved anticancer drugs does not currently exist. Partial information is available from multiple sources, including regulatory authorities, national formularies and scientific agencies. Many such data sources include drugs used in oncology for supportive care, diagnostic or other non-antineoplastic uses. We describe a methodology to combine and cleanse relevant data from multiple sources to produce an open access database of drugs licensed specifically for therapeutic antineoplastic purposes. The resulting list is provided as an open access database, (http://www.redo-project.org/cancer-drugs-db/), so that it may be used by researchers as input for further research projects, for example literature-based text mining for drug repurposing.