Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems

Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems

The use of testis tissue xenografting as a valuable tool to rescue endangered and genetically valuable individuals that die young or otherwise fail to produce sperm has been the subject of much interest. Although the technique has been successfully applied to a wide variety of species, little is kno...

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Main Authors: Paula C. Mota, João Ramalho-Santos, Stefan Schlatt
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.4061/2011/629409
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spelling doaj-86ae611cd7404b5990c8f21d10d9aedb2020-11-24T22:27:31ZengHindawi LimitedVeterinary Medicine International2042-00482011-01-01201110.4061/2011/629409629409Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model SystemsPaula C. Mota0João Ramalho-Santos1Stefan Schlatt2Center for Neuroscience and Cell Biology, Department of Life Sciences, University of Coimbra, P.O. Box/Apartado 3046, 3001-401 Coimbra, PortugalCenter for Neuroscience and Cell Biology, Department of Life Sciences, University of Coimbra, P.O. Box/Apartado 3046, 3001-401 Coimbra, PortugalCentre of Reproductive Medicine and Andrology, University of Münster, Domagkstraße 11, 48149 Münster, GermanyThe use of testis tissue xenografting as a valuable tool to rescue endangered and genetically valuable individuals that die young or otherwise fail to produce sperm has been the subject of much interest. Although the technique has been successfully applied to a wide variety of species, little is known about what determines the outcome. Furthermore, to improve the applicability of xenografting, new methods to preserve and transport testis tissue from valuable animals are emerging. However, one major issue remains: the application of xenografting implies the development of subsequent ART techniques to produce offspring from the recovered material. This paper focuses on these three aspects of testis tissue xenografting as a tool for rescuing endangered and valuable genetic pools.http://dx.doi.org/10.4061/2011/629409
collection DOAJ
language English
format Article
sources DOAJ
author Paula C. Mota
João Ramalho-Santos
Stefan Schlatt
spellingShingle Paula C. Mota
João Ramalho-Santos
Stefan Schlatt
Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
Veterinary Medicine International
author_facet Paula C. Mota
João Ramalho-Santos
Stefan Schlatt
author_sort Paula C. Mota
title Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
title_short Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
title_full Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
title_fullStr Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
title_full_unstemmed Xenografting as a Tool to Preserve Endangered Species: Outcomes and Challenges in Model Systems
title_sort xenografting as a tool to preserve endangered species: outcomes and challenges in model systems
publisher Hindawi Limited
series Veterinary Medicine International
issn 2042-0048
publishDate 2011-01-01
description The use of testis tissue xenografting as a valuable tool to rescue endangered and genetically valuable individuals that die young or otherwise fail to produce sperm has been the subject of much interest. Although the technique has been successfully applied to a wide variety of species, little is known about what determines the outcome. Furthermore, to improve the applicability of xenografting, new methods to preserve and transport testis tissue from valuable animals are emerging. However, one major issue remains: the application of xenografting implies the development of subsequent ART techniques to produce offspring from the recovered material. This paper focuses on these three aspects of testis tissue xenografting as a tool for rescuing endangered and valuable genetic pools.
url http://dx.doi.org/10.4061/2011/629409
work_keys_str_mv AT paulacmota xenograftingasatooltopreserveendangeredspeciesoutcomesandchallengesinmodelsystems
AT joaoramalhosantos xenograftingasatooltopreserveendangeredspeciesoutcomesandchallengesinmodelsystems
AT stefanschlatt xenograftingasatooltopreserveendangeredspeciesoutcomesandchallengesinmodelsystems
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