Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme
Abstract Glioblastoma multiforme (GBM) is the most common and aggressive malignant adult primary brain tumor. Despite surgical resection followed by radiotherapy and chemotherapy, the median survival rate is approximately 14 months. Although experimental therapies are in clinical trials for GBM, the...
Main Authors: | Sze Kiat Tan, Chiara Pastori, Clara Penas, Ricardo J. Komotar, Michael E. Ivan, Claes Wahlestedt, Nagi G. Ayad |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-018-0822-0 |
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