Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions
<p class="orbitalabstract">A simple, efficient, and green procedure for the solvent-free synthesis of 1-amido/thioamidoalkyl-2-naphthols by one-pot stirring of starting reactants at 100 °C has been introduced. By utilizing salicylic acid (SA) as the catalyst, the reaction of aryl ald...
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Universidade Federal de Mato Grosso do Sul
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doaj-86b610c72eba47b4866ba72d54296cb72021-07-07T19:22:39ZengUniversidade Federal de Mato Grosso do SulOrbital: The Electronic Journal of Chemistry1984-64282019-03-01111253210.17807/orbital.v11i1.1355538Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free ConditionsHassan Darbandi0Hamzeh Kiyani1Damghan UniversityDamghan University<p class="orbitalabstract">A simple, efficient, and green procedure for the solvent-free synthesis of 1-amido/thioamidoalkyl-2-naphthols by one-pot stirring of starting reactants at 100 °C has been introduced. By utilizing salicylic acid (SA) as the catalyst, the reaction of aryl aldehydes, 2-naphthol, and acetamide/benzamide/urea/thiourea were successfully performed, and 1-amido/thioamidoalkyl-2-naphthols were obtained in good to high isolated yields. The notable advantages of this method over some previous methods are the availability of catalyst, atom efficiency, not using any solvent for reaction, relatively green conditions, no need for catalyst synthesis, relatively shorter reaction times, and no specialized equipment (microwave or ultrasound) or purification techniques are needed.</p><p class="orbitalabstract"> </p><p class="orbitalabstract">DOI: <a href="http://dx.doi.org/10.17807/orbital.v11i1.1355">http://dx.doi.org/10.17807/orbital.v11i1.1355</a></p><p class="orbitalabstract"> </p>http://orbital.ufms.br/index.php/Chemistry/article/view/1355amidoalkylnaphtholsβ-naphtholthree-component reactionsalicylic acidsolvent-free |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hassan Darbandi Hamzeh Kiyani |
spellingShingle |
Hassan Darbandi Hamzeh Kiyani Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions Orbital: The Electronic Journal of Chemistry amidoalkylnaphthols β-naphthol three-component reaction salicylic acid solvent-free |
author_facet |
Hassan Darbandi Hamzeh Kiyani |
author_sort |
Hassan Darbandi |
title |
Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions |
title_short |
Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions |
title_full |
Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions |
title_fullStr |
Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions |
title_full_unstemmed |
Salicylic Acid-catalyzed Three-component Synthesis of 1-Amido/thioamidoalkyl-2-naphthols Under Solvent-free Conditions |
title_sort |
salicylic acid-catalyzed three-component synthesis of 1-amido/thioamidoalkyl-2-naphthols under solvent-free conditions |
publisher |
Universidade Federal de Mato Grosso do Sul |
series |
Orbital: The Electronic Journal of Chemistry |
issn |
1984-6428 |
publishDate |
2019-03-01 |
description |
<p class="orbitalabstract">A simple, efficient, and green procedure for the solvent-free synthesis of 1-amido/thioamidoalkyl-2-naphthols by one-pot stirring of starting reactants at 100 °C has been introduced. By utilizing salicylic acid (SA) as the catalyst, the reaction of aryl aldehydes, 2-naphthol, and acetamide/benzamide/urea/thiourea were successfully performed, and 1-amido/thioamidoalkyl-2-naphthols were obtained in good to high isolated yields. The notable advantages of this method over some previous methods are the availability of catalyst, atom efficiency, not using any solvent for reaction, relatively green conditions, no need for catalyst synthesis, relatively shorter reaction times, and no specialized equipment (microwave or ultrasound) or purification techniques are needed.</p><p class="orbitalabstract"> </p><p class="orbitalabstract">DOI: <a href="http://dx.doi.org/10.17807/orbital.v11i1.1355">http://dx.doi.org/10.17807/orbital.v11i1.1355</a></p><p class="orbitalabstract"> </p> |
topic |
amidoalkylnaphthols β-naphthol three-component reaction salicylic acid solvent-free |
url |
http://orbital.ufms.br/index.php/Chemistry/article/view/1355 |
work_keys_str_mv |
AT hassandarbandi salicylicacidcatalyzedthreecomponentsynthesisof1amidothioamidoalkyl2naphtholsundersolventfreeconditions AT hamzehkiyani salicylicacidcatalyzedthreecomponentsynthesisof1amidothioamidoalkyl2naphtholsundersolventfreeconditions |
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1721314670683357184 |