Importance and Considerations of Antibody Engineering in Antibody-Drug Conjugates Development from a Clinical Pharmacologist’s Perspective

Antibody-drug conjugates (ADCs) appear to be in a developmental boom, with five FDA approvals in the last two years and a projected market value of over $4 billion by 2024. Major advancements in the engineering of these novel cytotoxic drug carriers have provided a few early success stories. Althoug...

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Bibliographic Details
Main Authors: Andrew T. Lucas, Amber Moody, Allison N. Schorzman, William C. Zamboni
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/10/3/30