5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

Abstract Visual cortical areas show enhanced tactile responses in blind individuals, resulting in improved behavioral performance. Induction of unilateral vision loss in adult mice, by monocular enucleation (ME), is a validated model for such cross-modal brain plasticity. A delayed whisker-driven ta...

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Bibliographic Details
Main Authors: Nathalie Lombaert, Maroussia Hennes, Sara Gilissen, Giel Schevenels, Laetitia Aerts, Ria Vanlaer, Lieve Geenen, Ann Van Eeckhaut, Ilse Smolders, Julie Nys, Lutgarde Arckens
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Molecular Brain
Subjects:
Brain plasticity
Visual cortex
Adult mice
Monocular enucleation
Neuromodulator
Serotonin
Online Access:http://link.springer.com/article/10.1186/s13041-018-0404-5

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