Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties

Abstract Objectives: To evaluate the radiopacity of Biodentine (BD) and BD associated with 15% calcium tungstate (BDCaWO4) or zirconium oxide (BDZrO2), by using conventional and digital radiography systems, and their physicochemical and biological properties. Materials and Methods: Radiopacity was...

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Main Authors: Victor Manuel Ochoa-Rodríguez, Mario Tanomaru-Filho, Elisandra Marcia Rodrigues, Juliane Maria Guerreiro-Tanomaru, Rubens Spin-Neto, Gisele Faria
Format: Article
Language:English
Published: University of São Paulo 2019-04-01
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572019000100439&lng=en&tlng=en
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spelling doaj-86cf318e0eb14bf8b20585f24dd87e5e2020-11-24T20:52:32ZengUniversity of São PauloJournal of Applied Oral Science1678-77652019-04-0127010.1590/1678-7757-2018-0429S1678-77572019000100439Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological propertiesVictor Manuel Ochoa-RodríguezMario Tanomaru-FilhoElisandra Marcia RodriguesJuliane Maria Guerreiro-TanomaruRubens Spin-NetoGisele FariaAbstract Objectives: To evaluate the radiopacity of Biodentine (BD) and BD associated with 15% calcium tungstate (BDCaWO4) or zirconium oxide (BDZrO2), by using conventional and digital radiography systems, and their physicochemical and biological properties. Materials and Methods: Radiopacity was evaluated by taking radiographs of cement specimens (n=8) using occlusal film, photostimulable phosphor plates or digital sensors. Solubility, setting time, pH, cytocompatibility and osteogenic potential were also evaluated. Data were analyzed using one-way ANOVA and Tukey post-test or two-way ANOVA and Bonferroni post-test (α=0.05). Results: BD radiopacity was lower than 3 mm Al, while BD ZrO2 and BD CaWO4 radiopacity was higher than 3 mm Al in all radiography systems. The cements showed low solubility, except for BDCaWO4. All cements showed alkaline pH and setting time lower than 34 minutes. MTT and NR assays revealed that cements had greater or similar cytocompatibility in comparison with control. The ALP activity in all groups was similar or greater than the control. All cements induced greater production of mineralized nodules than control. Conclusions: Addition of 15% ZrO2 or CaWO4 was sufficient to increase the radiopacity of BD to values higher than 3 mm Al. BD associated with radiopacifiers showed suitable properties of setting time, pH and solubility, except for BDCaWO4, which showed the highest solubility. All cements had cytocompatibility and potential to induce mineralization in Saos-2 cells. The results showed that adding 15% ZrO2 increases the radiopacity of BD, allowing its radiography detection without altering its physicochemical and biological properties.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572019000100439&lng=en&tlng=enDental cementsDental digital radiographyEndodonticsMaterials testingPhysicochemical analysis
collection DOAJ
language English
format Article
sources DOAJ
author Victor Manuel Ochoa-Rodríguez
Mario Tanomaru-Filho
Elisandra Marcia Rodrigues
Juliane Maria Guerreiro-Tanomaru
Rubens Spin-Neto
Gisele Faria
spellingShingle Victor Manuel Ochoa-Rodríguez
Mario Tanomaru-Filho
Elisandra Marcia Rodrigues
Juliane Maria Guerreiro-Tanomaru
Rubens Spin-Neto
Gisele Faria
Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
Journal of Applied Oral Science
Dental cements
Dental digital radiography
Endodontics
Materials testing
Physicochemical analysis
author_facet Victor Manuel Ochoa-Rodríguez
Mario Tanomaru-Filho
Elisandra Marcia Rodrigues
Juliane Maria Guerreiro-Tanomaru
Rubens Spin-Neto
Gisele Faria
author_sort Victor Manuel Ochoa-Rodríguez
title Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
title_short Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
title_full Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
title_fullStr Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
title_full_unstemmed Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
title_sort addition of zirconium oxide to biodentine increases radiopacity and does not alter its physicochemical and biological properties
publisher University of São Paulo
series Journal of Applied Oral Science
issn 1678-7765
publishDate 2019-04-01
description Abstract Objectives: To evaluate the radiopacity of Biodentine (BD) and BD associated with 15% calcium tungstate (BDCaWO4) or zirconium oxide (BDZrO2), by using conventional and digital radiography systems, and their physicochemical and biological properties. Materials and Methods: Radiopacity was evaluated by taking radiographs of cement specimens (n=8) using occlusal film, photostimulable phosphor plates or digital sensors. Solubility, setting time, pH, cytocompatibility and osteogenic potential were also evaluated. Data were analyzed using one-way ANOVA and Tukey post-test or two-way ANOVA and Bonferroni post-test (α=0.05). Results: BD radiopacity was lower than 3 mm Al, while BD ZrO2 and BD CaWO4 radiopacity was higher than 3 mm Al in all radiography systems. The cements showed low solubility, except for BDCaWO4. All cements showed alkaline pH and setting time lower than 34 minutes. MTT and NR assays revealed that cements had greater or similar cytocompatibility in comparison with control. The ALP activity in all groups was similar or greater than the control. All cements induced greater production of mineralized nodules than control. Conclusions: Addition of 15% ZrO2 or CaWO4 was sufficient to increase the radiopacity of BD to values higher than 3 mm Al. BD associated with radiopacifiers showed suitable properties of setting time, pH and solubility, except for BDCaWO4, which showed the highest solubility. All cements had cytocompatibility and potential to induce mineralization in Saos-2 cells. The results showed that adding 15% ZrO2 increases the radiopacity of BD, allowing its radiography detection without altering its physicochemical and biological properties.
topic Dental cements
Dental digital radiography
Endodontics
Materials testing
Physicochemical analysis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572019000100439&lng=en&tlng=en
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