Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution

Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution

<p>Abstract</p> <p>Background</p> <p>New high-throughput sequencing technologies promise a very sensitive and high-resolution analysis of DNA methylation patterns in quantitative terms. However, a detailed and comprehensive comparison with existing validated DNA methyla...

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Bibliographic Details
Main Authors: Suerbaum Sebastian, Lamprecht Stella, Haeussler Katrin, Hasemeier Britta, Albat Cord, Potapova Anna, Kreipe Hans, Lehmann Ulrich
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/6

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