Evolution of the vertebrate insulin receptor substrate (Irs) gene family
Abstract Background Insulin receptor substrate (Irs) proteins are essential for insulin signaling as they allow downstream effectors to dock with, and be activated by, the insulin receptor. A family of four Irs proteins have been identified in mice, however the gene for one of these, IRS3, has been...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-06-01
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| Series: | BMC Evolutionary Biology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12862-017-0994-z |