Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus

Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus

Hemophagocytic syndrome (HPS) is characterized by the activation of histiocytes with prominent hemophagocytosis in bone marrow and other reticuloendothelial systems. It has two forms: primary and secondary. The precise pathogenesis of HPS is unclear but a dysregulation of macrophage–lymphocyte inter...

Full description

Bibliographic Details
Main Authors: Bushra Alblewi, Iqbal A. Bukhari, Manal Hasan, Abdulaziz Alzahani, Raed Bukhari, Layla Bashawri, Muhammad Al Shawarby
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Dermatology and Dermatologic Surgery
Subjects:
Hemophagocytic syndrome
Acute systemic lupus erythematosus
Acute pancreatitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352241014000073
id doaj-87097892a1e54c04a0b9de23dee244aa
record_format Article
spelling doaj-87097892a1e54c04a0b9de23dee244aa2020-11-25T01:57:16ZengWolters Kluwer Medknow PublicationsJournal of Dermatology and Dermatologic Surgery2352-24102014-01-01181353710.1016/j.jdds.2014.03.004Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosusBushra Alblewi0Iqbal A. Bukhari1Manal Hasan2Abdulaziz Alzahani3Raed Bukhari4Layla Bashawri5Muhammad Al Shawarby6Dermatology Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaDermatology Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaInternal Medicine Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaDermatology Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaInternal Medicine Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaPathology Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaPathology Department, College of Medicine, University of Dammam and King Fahd Hospital of the University, Dammam, Saudi ArabiaHemophagocytic syndrome (HPS) is characterized by the activation of histiocytes with prominent hemophagocytosis in bone marrow and other reticuloendothelial systems. It has two forms: primary and secondary. The precise pathogenesis of HPS is unclear but a dysregulation of macrophage–lymphocyte interactions with subsequent increases in the levels of both T-cell-derived and macrophage-derived cytokines has been suggested. Cardinal symptoms of HPS are prolonged high fever, hepatosplenomegaly, cytopenias, lymphadenopathy and neurological symptoms. In this report, we present a case Systemic Lupus Erythematosus associated with HPS and acute pancreatitis.http://www.sciencedirect.com/science/article/pii/S2352241014000073Hemophagocytic syndromeAcute systemic lupus erythematosusAcute pancreatitis
collection DOAJ
language English
format Article
sources DOAJ
author Bushra Alblewi
Iqbal A. Bukhari
Manal Hasan
Abdulaziz Alzahani
Raed Bukhari
Layla Bashawri
Muhammad Al Shawarby
spellingShingle Bushra Alblewi
Iqbal A. Bukhari
Manal Hasan
Abdulaziz Alzahani
Raed Bukhari
Layla Bashawri
Muhammad Al Shawarby
Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
Journal of Dermatology and Dermatologic Surgery
Hemophagocytic syndrome
Acute systemic lupus erythematosus
Acute pancreatitis
author_facet Bushra Alblewi
Iqbal A. Bukhari
Manal Hasan
Abdulaziz Alzahani
Raed Bukhari
Layla Bashawri
Muhammad Al Shawarby
author_sort Bushra Alblewi
title Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
title_short Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
title_full Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
title_fullStr Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
title_full_unstemmed Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
title_sort hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus
publisher Wolters Kluwer Medknow Publications
series Journal of Dermatology and Dermatologic Surgery
issn 2352-2410
publishDate 2014-01-01
description Hemophagocytic syndrome (HPS) is characterized by the activation of histiocytes with prominent hemophagocytosis in bone marrow and other reticuloendothelial systems. It has two forms: primary and secondary. The precise pathogenesis of HPS is unclear but a dysregulation of macrophage–lymphocyte interactions with subsequent increases in the levels of both T-cell-derived and macrophage-derived cytokines has been suggested. Cardinal symptoms of HPS are prolonged high fever, hepatosplenomegaly, cytopenias, lymphadenopathy and neurological symptoms. In this report, we present a case Systemic Lupus Erythematosus associated with HPS and acute pancreatitis.
topic Hemophagocytic syndrome
Acute systemic lupus erythematosus
Acute pancreatitis
url http://www.sciencedirect.com/science/article/pii/S2352241014000073
work_keys_str_mv AT bushraalblewi hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT iqbalabukhari hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT manalhasan hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT abdulazizalzahani hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT raedbukhari hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT laylabashawri hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
AT muhammadalshawarby hemophagocyticsyndromeandacutepancreatitisinacutesystemiclupuserythematosus
_version_ 1724975193240109056

Similar Items