Extinction blunts paraventricular thalamic contributions to heroin relapse

Extinction blunts paraventricular thalamic contributions to heroin relapse

Summary: Here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (PVT) to nucleus accumbens (NAc) pathway in aversion and heroin relapse in two different heroin self-administration models in rats. In one model, rats undergo forced abstinence in the...

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Bibliographic Details
Main Authors:	Giuseppe Giannotti, Sheng Gong, Nicholas Fayette, Jasper A. Heinsbroek, James E. Orfila, Paco S. Herson, Christopher P. Ford, Jamie Peters
Format:	Article
Language:	English
Published:	Elsevier 2021-08-01
Series:	Cell Reports
Subjects:	paraventricular thalamus nucleus accumbens heroin abstinence extinction relapse
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124721010433

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