Preparation and characterization of paclitaxel palmitate albumin nanoparticles with high loading efficacy: an in vitro and in vivo anti-tumor study in mouse models

Preparation and characterization of paclitaxel palmitate albumin nanoparticles with high loading efficacy: an in vitro and in vivo anti-tumor study in mouse models

Background Combination of the prodrug technique with an albumin nano drug-loaded system is a novel promising approach for cancer treatment. However, the long-lasting and far-reaching challenge for the treatment of cancers lies in how to construct the albumin nanometer drug delivery system with lead...

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Bibliographic Details
Main Authors: Hang Chen, Sifan Huang, Heyi Wang, Xinmei Chen, Haiyan Zhang, Youfa Xu, Wei Fan, Yun Pan, Qiuyan Wen, Zhizhe Lin, Xuena Wang, Yongwei Gu, Baoyue Ding, Jianming Chen, Xin Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
paclitaxel palmitate
albumin nanoparticles
toxicity
tissue distribution
pharmacodynamics
Online Access:http://dx.doi.org/10.1080/10717544.2021.1921078

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