Ethanol-Induced Autophagy in Sertoli Cells Is Specifically Marked at Androgen-Dependent Stages of the Spermatogenic Cycle: Potential Mechanisms and Implications

Ethanol-Induced Autophagy in Sertoli Cells Is Specifically Marked at Androgen-Dependent Stages of the Spermatogenic Cycle: Potential Mechanisms and Implications

In a recent study, we reported that acute ethanol exposure enhanced autophagy in Sertoli cells (SCs) of adult rats. However, further research is needed to clarify the specific spermatogenic stage exhibiting the highest autophagic response, the mechanisms behind such specificity, and the related rele...

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Bibliographic Details
Main Authors: Akio Horibe, Nabil Eid, Yuko Ito, Yoshinori Otsuki, Yoichi Kondo
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
ethanol
autophagy
LC3
apoptosis
Sertoli
androgen receptor
PINK1
sperm retention
spermatogenic cycle
mitophagy
lipophagy
LAP
infertility
Online Access:http://www.mdpi.com/1422-0067/20/1/184

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