Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword

Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword

First described for their metabolic and immunosuppressive effects, glucocorticoids are widely prescribed in clinical settings of inflammation. However, glucocorticoids are also potent inducers of apoptosis in many cell types and tissues. This review will focus on the established mechanisms of glucoc...

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Bibliographic Details
Main Authors: Amanda L. Gruver-Yates, John A. Cidlowski
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Cells
Subjects:
glucocorticoids
glucocorticoid receptors
apoptosis
Online Access:http://www.mdpi.com/2073-4409/2/2/202

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