Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Hepatitis C virus (HCV) infection is a leading cause of liver transplantation and there is an urgent need to develop therapies to reduce rates of HCV infection of transplanted livers. Approved therapeutics for HCV are poorly tolerated and are of limited efficacy in this patient population. Human mon...

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Bibliographic Details
Main Authors: Trevor J Morin, Teresa J Broering, Brett A Leav, Barbra M Blair, Kirk J Rowley, Elisabeth N Boucher, Yang Wang, Peter S Cheslock, Michael Knauber, David B Olsen, Steve W Ludmerer, Gyongyi Szabo, Robert W Finberg, Robert H Purcell, Robert E Lanford, Donna M Ambrosino, Deborah C Molrine, Gregory J Babcock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3431327?pdf=render

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