A novel non genomic glucocorticoid signaling mediated by a membrane palmitoylated glucocorticoid receptor cross talks with GnRH in gonadotrope cells

Abstract Glucocorticoid hormones (GC) are the main stress mediators associated with reproductive disorders. GC exert their effects through activation of the glucocorticoid receptor (GR) principally acting as a transcription factor. Beside well-established GR-mediated genomic actions, several lines o...

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Bibliographic Details
Main Authors: Mohsen Ayrout, Violaine Simon, Valérie Bernard, Nadine Binart, Joëlle Cohen-Tannoudji, Marc Lombès, Stéphanie Chauvin
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01777-2

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