Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

Here, via a metagenomics analysis of population-based and disease cohorts, Vich Vila et al. study the impact of 41 commonly used medications on the taxonomic structures, metabolic potential and resistome of the gut microbiome, underscoring the importance of correcting for multiple drug use in microb...

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Main Authors:	Arnau Vich Vila, Valerie Collij, Serena Sanna, Trishla Sinha, Floris Imhann, Arno R. Bourgonje, Zlatan Mujagic, Daisy M. A. E. Jonkers, Ad A. M. Masclee, Jingyuan Fu, Alexander Kurilshikov, Cisca Wijmenga, Alexandra Zhernakova, Rinse K. Weersma
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-01-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-14177-z

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spelling	doaj-877318e8d3ad4c1b9c92da30248a0cb02021-05-11T08:45:02ZengNature Publishing GroupNature Communications2041-17232020-01-0111111110.1038/s41467-019-14177-zImpact of commonly used drugs on the composition and metabolic function of the gut microbiotaArnau Vich Vila0Valerie Collij1Serena Sanna2Trishla Sinha3Floris Imhann4Arno R. Bourgonje5Zlatan Mujagic6Daisy M. A. E. Jonkers7Ad A. M. Masclee8Jingyuan Fu9Alexander Kurilshikov10Cisca Wijmenga11Alexandra Zhernakova12Rinse K. Weersma13Dept. of Gastroenterology and Hepatology, University of Groningen and University Medical Center GroningenDept. of Gastroenterology and Hepatology, University of Groningen and University Medical Center GroningenDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Gastroenterology and Hepatology, University of Groningen and University Medical Center GroningenDept. of Gastroenterology and Hepatology, University of Groningen and University Medical Center GroningenDivision Gastroenterology Hepatology, Maastricht University Medical CenterDivision Gastroenterology Hepatology, Maastricht University Medical CenterDivision Gastroenterology Hepatology, Maastricht University Medical CenterDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Genetics, University of Groningen and University Medical Center GroningenDept. of Gastroenterology and Hepatology, University of Groningen and University Medical Center GroningenHere, via a metagenomics analysis of population-based and disease cohorts, Vich Vila et al. study the impact of 41 commonly used medications on the taxonomic structures, metabolic potential and resistome of the gut microbiome, underscoring the importance of correcting for multiple drug use in microbiome studies.https://doi.org/10.1038/s41467-019-14177-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Arnau Vich Vila Valerie Collij Serena Sanna Trishla Sinha Floris Imhann Arno R. Bourgonje Zlatan Mujagic Daisy M. A. E. Jonkers Ad A. M. Masclee Jingyuan Fu Alexander Kurilshikov Cisca Wijmenga Alexandra Zhernakova Rinse K. Weersma
spellingShingle	Arnau Vich Vila Valerie Collij Serena Sanna Trishla Sinha Floris Imhann Arno R. Bourgonje Zlatan Mujagic Daisy M. A. E. Jonkers Ad A. M. Masclee Jingyuan Fu Alexander Kurilshikov Cisca Wijmenga Alexandra Zhernakova Rinse K. Weersma Impact of commonly used drugs on the composition and metabolic function of the gut microbiota Nature Communications
author_facet	Arnau Vich Vila Valerie Collij Serena Sanna Trishla Sinha Floris Imhann Arno R. Bourgonje Zlatan Mujagic Daisy M. A. E. Jonkers Ad A. M. Masclee Jingyuan Fu Alexander Kurilshikov Cisca Wijmenga Alexandra Zhernakova Rinse K. Weersma
author_sort	Arnau Vich Vila
title	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
title_short	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
title_full	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
title_fullStr	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
title_full_unstemmed	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
title_sort	impact of commonly used drugs on the composition and metabolic function of the gut microbiota
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-01-01
description	Here, via a metagenomics analysis of population-based and disease cohorts, Vich Vila et al. study the impact of 41 commonly used medications on the taxonomic structures, metabolic potential and resistome of the gut microbiome, underscoring the importance of correcting for multiple drug use in microbiome studies.
url	https://doi.org/10.1038/s41467-019-14177-z
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Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

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