RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression

Lipogenesis plays a critical role in the growth and metastasis of tumors, which is becoming an attractive target for anti-tumor drugs. RA-XII, one of the cyclopeptide glycosides isolated from <i>Rubia yunnanensis</i>, exerts anti-tumor effects on liver cancer. However, the underlying mec...

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Bibliographic Details
Main Authors: Di Guo, Yurong Wang, Jing Wang, Lihua Song, Zhe Wang, Bingyu Mao, Ninghua Tan
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/9/1829

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