High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material

High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material

Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor sur...

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Bibliographic Details
Main Authors: Felix F. Loeffler, Tobias C. Foertsch, Roman Popov, Daniela S. Mattes, Martin Schlageter, Martyna Sedlmayr, Barbara Ridder, Florian-Xuan Dang, Clemens von Bojničić-Kninski, Laura K. Weber, Andrea Fischer, Juliane Greifenstein, Valentina Bykovskaya, Ivan Buliev, F. Ralf Bischoff, Lothar Hahn, Michael A. R. Meier, Stefan Bräse, Annie K. Powell, Teodor Silviu Balaban, Frank Breitling, Alexander Nesterov-Mueller
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11844
Description
Summary:Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor surfaces.
ISSN:2041-1723

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