RNA-seq Characterization of Melanoma Phenotype Switch in 3D Collagen after p38 MAPK Inhibitor Treatment
Melanoma phenotype plasticity underlies tumour dissemination and resistance to therapy, yet its regulation is incompletely understood. In vivo switching between a more differentiated, proliferative phenotype and a dedifferentiated, invasive phenotype is directed by the tumour microenvironment. We fo...
Main Authors: | Vladimír Čermák, Aneta Škarková, Ladislav Merta, Veronika Kolomazníková, Veronika Palušová, Stjepan Uldrijan, Daniel Rösel, Jan Brábek |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/3/449 |
Similar Items
-
Sustained Inflammatory Signalling through Stat1/Stat2/IRF9 Is Associated with Amoeboid Phenotype of Melanoma Cells
by: Aneta Gandalovičová, et al.
Published: (2020-08-01) -
Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells
by: Angela Leo, et al.
Published: (2021-07-01) -
Increased Level of Long Non-Coding RNA MALAT1 is a Common Feature of Amoeboid Invasion
by: Ladislav Merta, et al.
Published: (2020-05-01) -
Reduced WNT5A signaling in melanoma cells favors an amoeboid mode of invasion
by: Njainday Pulo Jobe, et al.
Published: (2021-07-01) -
ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma
by: Ewa Aladowicz, et al.
Published: (2020-11-01)