Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers
There is substantial evidence for a role in cancer of the bioactive lipid sphingosine 1-phosphate (S1P), the enzyme sphingosine kinase 1 (that catalyses S1P formation) and S1P-specific G protein coupled receptors. This perspective highlights recent findings demonstrating that sphingosine kinase 1 a...
Main Authors: | Susan ePyne, Joanne eEdwards, Jan eOhotski, Nigel John Pyne |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-12-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00168/full |
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