Brain Health: Translating Scientific Evidence Into Clinical Practice in Multiple Sclerosis

• Main Authors: Per Soelberg Sørensen, Wiendl, Andreas Lysandropoulos, Andrew Chan
• Format: Article
• Language: English
• Published: European Medical Journal 2016-07-01
• Series: European Medical Journal Neurology
• Subjects: EAN; European Association of Neurology
• Online Access: http://emjreviews.com/wp-content/uploads/Brain-Health-Translating-Scientific-Evidence-Into-Clinical-Practice-in-Multiple-Sclerosis.pdf

Brain volume loss (BVL) progresses more rapidly in patients with multiple sclerosis (MS) than in healthy individuals, and brain atrophy begins early in the course of the disease. The objective of this symposium was to emphasise the importance of care and preservation of the brain within treatment protocols for MS so that early and appropriate management can be initiated to preserve brain volume and function. Prof Per Solberg Sørensen chaired the symposium and welcomed the speakers. Prof Heinz Wiendl gave a presentation on BVL in MS and described its underlying pathophysiology. Dr Andreas Lysandropoulos illustrated how information on BVL is clinically relevant and can be taken from clinical studies to assist clinical practice and decision-making. The final presentation was given by Prof Andrew Chan who highlighted the important role of brain atrophy in decision-making for early treatment and presented recent data for two treatments for MS: teriflunomide and the monoclonal antibody alemtuzumab. The symposium was concluded by a short question and answer session.