Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina
The aim of this study was to estimate the cost-effectiveness of reducing tegumentary leishmaniasis transmission using insecticide-impregnated clothing and curtains, and implementing training programs for early diagnosis. A societal perspective was adopted, with outcomes assessed in terms of costs pe...
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
2013-12-01
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doaj-87db9626833249158aef49f509859dae2020-11-24T23:23:50ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-44642013-12-0129122459247210.1590/0102-311X00172512S0102-311X2013001200011Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in ArgentinaPablo Wenceslao Orellano0Nestor Vazquez1Oscar Daniel Salomon2Instituto Nacional de Medicina TropicalUniversidad de Buenos AiresInstituto Nacional de Medicina TropicalThe aim of this study was to estimate the cost-effectiveness of reducing tegumentary leishmaniasis transmission using insecticide-impregnated clothing and curtains, and implementing training programs for early diagnosis. A societal perspective was adopted, with outcomes assessed in terms of costs per disability adjusted life years (DALY). Simulation was structured as a Markov model and costs were expressed in American dollars (US$). The incremental cost-effectiveness ratio of each strategy was calculated. One-way and multivariate sensitivity analyses were performed. The incremental cost-effectiveness ratio for early diagnosis strategy was estimated at US$ 156.46 per DALY averted, while that of prevention of transmission with insecticide-impregnated curtains and clothing was US$ 13,155.52 per DALY averted. Both strategies were more sensitive to the natural incidence of leishmaniasis, to the effectiveness of mucocutaneous leishmaniasis treatment and to the cost of each strategy. Prevention of vectorial transmission and early diagnosis have proved to be cost-effective measures.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001200011&lng=en&tlng=enLeishmaniasisPrevención de EnfermedadesAvaliación de Costo-Efectividad |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pablo Wenceslao Orellano Nestor Vazquez Oscar Daniel Salomon |
spellingShingle |
Pablo Wenceslao Orellano Nestor Vazquez Oscar Daniel Salomon Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina Cadernos de Saúde Pública Leishmaniasis Prevención de Enfermedades Avaliación de Costo-Efectividad |
author_facet |
Pablo Wenceslao Orellano Nestor Vazquez Oscar Daniel Salomon |
author_sort |
Pablo Wenceslao Orellano |
title |
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina |
title_short |
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina |
title_full |
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina |
title_fullStr |
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina |
title_full_unstemmed |
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina |
title_sort |
cost-effectiveness of prevention strategies for american tegumentary leishmaniasis in argentina |
publisher |
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
series |
Cadernos de Saúde Pública |
issn |
1678-4464 |
publishDate |
2013-12-01 |
description |
The aim of this study was to estimate the cost-effectiveness of reducing tegumentary leishmaniasis transmission using insecticide-impregnated clothing and curtains, and implementing training programs for early diagnosis. A societal perspective was adopted, with outcomes assessed in terms of costs per disability adjusted life years (DALY). Simulation was structured as a Markov model and costs were expressed in American dollars (US$). The incremental cost-effectiveness ratio of each strategy was calculated. One-way and multivariate sensitivity analyses were performed. The incremental cost-effectiveness ratio for early diagnosis strategy was estimated at US$ 156.46 per DALY averted, while that of prevention of transmission with insecticide-impregnated curtains and clothing was US$ 13,155.52 per DALY averted. Both strategies were more sensitive to the natural incidence of leishmaniasis, to the effectiveness of mucocutaneous leishmaniasis treatment and to the cost of each strategy. Prevention of vectorial transmission and early diagnosis have proved to be cost-effective measures. |
topic |
Leishmaniasis Prevención de Enfermedades Avaliación de Costo-Efectividad |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2013001200011&lng=en&tlng=en |
work_keys_str_mv |
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